Abstract View

Author(s): Gayatree

Email(s): Gayatri.deshlahre@gmail.com

Address: University Institute of Pharmacy, Pr. RavishankarShukla University, Raipur - 492 010, India.

Published In:   Volume - 29,      Issue - 1,     Year - 2016

DOI: Not Available

ABSTRACT:
Development of phytovesicle is a new approach for plant extracts and active components. It is a type of novel drug delivery systems (NDDS). The other available approaches for novel herbal formulations like polymeric nanoparticles, nanocapsules, liposomes, phytosomes, nanoemulsions, microsphere, niosomes, planterosomes, cubosomes, transferosomes, and ethosomes has been reported using bioactive and plant extracts. Many plant extracts and phytoconstituents, despite having excellent bioactivity in vitro, but have less or no in vivo actions due to their poor lipid or water solubility or improper molecular size or destruction in gut. Drug delivery system for polyphenolic phytoconstituents (phytosomes) was prepared by complexing polyphenolic phytoconstituents with phospholipid mainly phosphatidylcholine which bind components to each other on a molecular level. Bioavailability is enhanced due to their capacity to cross the lipid rich bio-membranes and to protect the valuable components of the herbal extract from destruction by digestive secretions and gut bacteria. Phytovesicle have the capacity to deliver the standardized plant extracts and phytoconstituents through several routes of drug administration. Phytovesicles absorption in GIT is greater resulting in increased plasma level than individual component. Phytovesicles act as bridge between novel delivery system and conventional delivery system. Phospholipids molecule acting as vital carrier made up of water soluble head and two fat soluble tails, due to this nature they possess dual solubility and thus acting as an effective emulsifier. Phytosome represents a promising vesicular drug delivery system to deliver therapeutic compounds for a wide range of possible applications.

Cite this article:
Gayatree (2016). Development of Phytovesicles of Plant Constituents via Complexation with Phospholipid. Journal of Ravishankar University (Part-B: Science), 29(1), pp.156-157.


References not available.

Related Images:



Recent Images



Chlorpyrifos Mediated Amendment in Protein Profiling of Bacillus spp.
Structural, Compositional and Photoluminescence Studies of Li4SrCa(SiO4)2: Eu3+ Red Phosphor Synthesized by Solid State Reaction Method
Formulation and Characterization of Magnetically Responsive Mesalamine Microspheres for Colon Targeting
Development of Non-Invasive Technique for Heart Rate Detection Using Facial Videos
Human Part Semantic Segmentation Using CDGNET Architecture for Human Activity Recognition
Lifestyle Modification Therapy and its Effect on Weight Status of Non-Alcoholic Male Liver Disease Patients
Exploring Life Cycle Analysis in Developing Sustainable Communities in Chhattisgarh
Monitoring the Concentration of Lead in the Industrial Wastewater of Baloda Bazar District
Impact of Climate Change on Paddy Yield in Bastar District of Chhattisgarh
Chemical Pollutants: A Concern to The Environment

Tags


Recomonded Articles:

Author(s): Preety Shukla; Anindita Roy; Shubha R Sharma

DOI:         Access: Open Access Read More

Author(s): Dinesh Kumar Sharma; Bhabani S Nayak

DOI:         Access: Open Access Read More

Author(s): Rahul Singh; Gunjan Kalyani; Neeraj Kumar Verma; Kamlesh Kumar Dadsena; Rashmi Dwivedi; Nishtha Vaidya; Atanu Kumar Pati; Mitashree Mitra

DOI:         Access: Open Access Read More

Author(s): Richa Shri; Kundan Singh Bora; Abhishek Bhanot; Rahul Kumar; Amit Kumar

DOI:         Access: Open Access Read More

Author(s): Ganjare Anjali; Raut Nishikant

DOI:         Access: Open Access Read More

Author(s): Sakshi Tiwari Bajaj; S K Taunk; G S Tomar

DOI:         Access: Open Access Read More

Author(s): Kartik T Nakhate; Hemant R Badwaik; Ajazuddin

DOI:         Access: Open Access Read More

Author(s): Manish M. Wanjari; Indu Sikarwar; Yadu Nandan Dey; Ajay Sharma; Sudesh Gaidhani; Ankush Jadhav

DOI:         Access: Open Access Read More

Author(s): Debarshi Kar Mahapatra; Manish Kamble; Ruchi Shivhare; Kavita Pandey

DOI:         Access: Open Access Read More

Author(s): M N Motiwala; R A Gupta; N G Dumore; U N Mahajan; K R Danao

DOI:         Access: Open Access Read More

Author(s): PR Shende; PR Itankar; SK Prasad

DOI:         Access: Open Access Read More