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Author(s): Debarshi Kar Mahapatra, Manish Kamble, Ruchi Shivhare, Kavita Pandey

Email(s): mahapatradebarshi@gmail.com

Address: Department of Pharmaceutical Chemistry, Kamla Nehru College of Pharmacy, Nagpur 440026, India
Department of Pharmacognosy, Kamla Nehru College of Pharmacy, Nagpur - 440026, India.

Published In:   Volume - 29,      Issue - 1,     Year - 2016

DOI:

ABSTRACT:
Tridax procumbens L. is a traditional plant known for its anti-inflammatory activity, however, many literatures have reported the potentiality, but the actual vital portion where the liable phytoconstituents are present is still debated. In order, to determine the same, in vitro anti-inflammatory activity of Tridax procumbens L. plant part (leaf, stem, root, and flower) extracts (aqueous, ethanol, methanol, chloroform and petroleum ether) were investigated by human red bold cell membrane stabilization (HRBCM) method. All the plant part extracts showed moderate to significantly high activity. The alcoholic leaf extract (ethanol and methanol) demonstrated noteworthy HRBCM stabilization activity at 200 ug/mL (69.68%, and 70.44%) compared to standard drug diclofenac sodium (81.37%). Moreover, the extracts displayed considerable anti- inflammatory potential. The result of the study revealed the traditional importance of this plant in inflammation.

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