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Author(s): Rakesh Tirkey

Email(s): rakeshtirkey99@gmail.com

Address: University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur - 492 010, India.

Published In:   Volume - 29,      Issue - 1,     Year - 2016

DOI: Not Available

ABSTRACT:
The present study was aimed to investigate Anti-diabetic and antioxidant activity of Xantolis tomentosa extract (Family: Sapotaceae). It is commonly found in the various north east and south regions of India. The aerial parts were collected, shade dried and extracted with ethanol using Soxhlet extractor. Anti-diabetic activity of ethanolic (EEXT) extracts of Xantolis tomentosa was carried out on Wistar albino rats. The observation showed The ethanolic extract of Xantolis tomentosa (200 and 400 mg/kg, p.o.) showed significant reduction (P< 0.05) of fasting blood glucose levels in streptozotocin induced typell diabetic rats on the 10 and 15 days. In the oral glucose tolerance test, the extract increased the glucose tolerance. It also brought about an increase in the body weight of diabetic rats. The extracts were also evaluated for antioxidant activity by free radical scavenging assay using DPPH and showed a prominent antioxidant activity but were comparatively lower than standard significantly (P < 0.05). Further studies are needed to be done to isolate the active phytoconstituents responsible for bringing the Anti-diabeticactivityand antioxidant activity.

Cite this article:
Tirkey (2016). Evaluation of Anti-Diabetic and Antioxidant Activity of Xantolis tomentosa Extract. Journal of Ravishankar University (Part-B: Science), 29(1), pp.196-197.


References not available.

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