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Author(s): Ankita Sahu, Manju Singh, Vishal Jain, Veenu Joshi, Amber Vyas

Email(s): ambervyas@gmail.com

Address: University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh
University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh
University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh
Centre of Basic Science, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh
University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh
*Corresponding author: ambervyas@gmail.com

Published In:   Volume - 36,      Issue - 2,     Year - 2023

DOI: 10.52228/JRUB.2023-36-2-1  

ABSTRACT:
Atopic Dermatitis (AD) is a complicated condition that places tremendous physiological and psychological strain on individuals. Natural products have long been used to cure diseases such as cancer, asthma, gastrointestinal disorders, neurological disorders, and infections. The study findings reveal that natural compounds, particularly quercetin, gallic acid, and ginsenosides, have promised preventive effects against atopic dermatitis. The study addresses the medicinal properties of bioactive compounds and emphasizes their ability to exert anti-inflammatory action. These compounds exhibit anti-inflammatory properties by reducing the quantity and functionality of various inflammatory cells such as cytokines neutrophils, monocytes, lymphocytes, Langerhans cells, interleukins (ILs, such as IL-1 IL-5, and IL-4, IL-13, and IL-31), TNF-α, TSLP, and IgE, etc. The studies would pave the way for the development of natural compounds specifically designed to treat atopic dermatitis in humans. Atopic dermatitis is routinely treated using bioactive and phytoconstituents derived from them. As a result, the review emphasizes recent advances in understanding the clinical characteristics, etiology, pathogenesis, treatment with bioactive compounds, and management of atopic dermatitis.

Cite this article:
Sahu, Singh, Jain, Joshi and Vyas (2023). Potential of Bioactive Compounds for Atopic Dermatitis. Journal of Ravishankar University (Part-B: Science), 36(2), pp. 1-18.DOI: https://doi.org/10.52228/JRUB.2023-36-2-1


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