Abstract View

Author(s): Reena Jamunkar, Deepak Sinha, Tarun Kumar Patle, Kamlesh Shrivas

Email(s): reenajamunkar@gmail.com

Address: Department of Chemistry, Government Nagarjuna Post Graduate College of Science, Raipur, CG-492010, India
Department of Chemistry, Government Nagarjuna Post Graduate College of Science, Raipur, CG-492010, India
Department of Chemistry, Pt. Sundarlal Sharma (Open) University, Chhattisgarh, Bilaspur-495009, India
School of Studies in Chemistry, Pt. Ravishanakar Shukla University, Raipur-492010, CG, India
*Corresponding Author: reenajamunkar@gmail.com

Published In:   Volume - 37,      Issue - 1,     Year - 2024

DOI: 10.52228/JRUB.2024-37-1-10  

Bioactive compounds obtained from plants, microorganisms and minerals show some specific properties like insecticidal, herbicidal, repellent, antifeedant and toxicant activities called bio pesticide. They have specific modes of action against different pests. Due to their environmental eco-friendly nature, low cost, economic effectiveness, less pollution, and target specific quality they are in high demand in agriculture compared to chemical or synthetic pesticides. Extraction, purification, identification and characterization of these compounds from the plants materials are found always challenging. There are various types of traditional and non-traditional methods of extraction have been proposed such as maceration, distillation, ultrasonic-assisted extraction, soxhlet extraction, enzyme assisted extraction, microwave assisted extraction, accelerated solvent extraction, etc. have been reported for extraction of bioactive ingredients from plants complex matrix samples. The chromatographic separation techniques like thin layer chromatography(TLC), high performance thin layer chromatography (HPTLC), high performance liquid chromatography (HPLC) and gas chromatographic (GC) are used for their separation followed by the identification in order to determine their structure with the help of UV-Vis, fluorescence, NMR spectrometry, Fourier transforms infra-red spectrometry (FTIR) and mass spectrometry (MS). This review summarized the extraction procedure, formulation of biopesticide, structural identification and their application in agriculture.

Cite this article:
Jamunkar, Sinha, Patle, and Shrivas (2024). A Review on Extraction, Identification and Application of Pesticidal Active Phytoderived Metabolites. Journal of Ravishankar University (Part-B: Science), 37(1), pp. 152-187. DOI:DOI: https://doi.org/10.52228/JRUB.2024-37-1-10


Abdollahdokht, D., Gao, Y., Faramarz, S., Poustforoosh, A., Abbasi, M. Asadikaram, G. and Nematollahi, M. H. (2022).                               Conventional agrochemicals towards nano‑biopesticides: an overview on recent advances. Chem. Biol. Technol.     Agric., 9.

Adedire, C. O. and Akinneye, J.O. (2004). Biological activity of tree marigold, Tithonia diversifolia, on cowpea seed     bruchid, Callosobruchus maculates. Ann. appl. Biol., 144,185-189.

Adesina, J. M. and Ofuya, T. I. (2015). Oviposition Deterrent and egg hatchability suppression of Secamone afzelii K.       Schum Leaf extract on Callosobruchus maculantus. Jorden J. Biol. Sci., 8.

Aktar, M. W., Sengupta, D., Chowdhury, A. (2009). Impact of pesticides use in agriculture: their benefits and    hazards. Interdisc Toxicol., 2, 1–12.

AlaraO.R., Abdurahman, N. H.,   Ukaegbu, C. I. (2018). Soxhlet extraction of phenolic compounds from Vernonia     cinerea leaves and its antioxidant activity. J. Appl. Res. Med. Aromat. Plants, 11, 12-17.

Alzagaa, B. G., Lacasa˜ na, M., Gardu˜ no, C. A., Barranco, M. R., Ballester, F., Rebagliato, M., Hernández, A.F. (2014).          Asystematic review of neurodevelopmental effects of prenatal and postnatal organophosphate pesticide exposure.            Toxicol. Lett., 230, 104–121.

Ambrosino, P., Fresa, R., Fogliano, V., Monti, S. M. and Ritieni, A. (1999). Extraction of  Azadirachtin A from neem seed      kernels by Supercritical Fluid and its evolution by HPLC and LC/MS. J. Agric. Food Chem.,47, 5252-5256.

Anikwe, J. C., Okelana, F. A., Mokwunye, I. U., and Oyedokun, A. Y. (2021). History and recent development of pesticide     usage on cocoa in Nigeria. Afric. J. Gen. Agric. 5, 211–219.

Arceusz, A., Occhipinti, A., Capuzzo, A., Maffei, M. E. (2013). Comparison of different extraction methods for the      determination of α- and _β-thujonein sage (Salvia officinalis L.) herbal tea. J. Sep. Sci., 36, 3130–3134.

Ayilara, M. S., Adeleke, B. S., Akinola, S. A., Fayose, C. A., Adeyemi, U. T., Gbadegesin, L. A., Omole, R. K., Johnson, R. M., Uthman, Q. O. and Babalola, O. O. (2023). Biopesticides as a promising alternative to synthetic pesticides: A    case for microbial pesticides, phytopesticides, and nanobiopesticides. Front. Microbiol., 14,1040901.

Baby, K. C., Vasudevan, R. T. (2013). Enzyme –Assisted extraction of bioingradients. Chem. Weekly, 10, 213-224.

Baldino, L., Scognamiglio, M., Reverchon, E.(2018). Extraction of rotenoids from Derris elliptica using super critical        CO2.    J.  Chem. Technol. Biotechnol., 93, 3656-3660.

Ban, D., Sladonja, B., Luki, M., Luki, I., Lušeti, V., Gani, K. K. e. and Žnidar, D. (2010). Comparison of pyrethrins         extraction methods efficiencies. Afr. J. Biotechnol., 9, 2702-2708.

Bisergaeva, R. A., Takaeva, M. A. and Sirieva1, Y. N. (2021). Extraction of eugenol, a natural product, and the preparation      of eugenol benzoate.  J. Phys. Conf. Ser., 1889, 022085.

Bharti, V. and Ibrahim, S. (2020).  Biopesticides: Production, Formulation and Application Systems. Int. J. Curr. Microbiol.   App. Sci, 9, 3931-3946.

Boadu, K. O., Tulashle, S. K., Anang, M. A., Kpan, J. D. (2011). Production of natural insecticide from neem leaves. Asian     J. Plant Sci. Res., 1, 33-38.

Bobade, S. N., Khyade, V. B. (2012). Detail study on the properties of Pongamia pinnata for the production of Biofuel. Res. J. Chem. Sci., 2, 16-26.

Bock, C. H., Ilan, D. I. S., Wedge, D. E., Cantrell, C. L. (2014) Identification of the antifungal compound, trans- cinnamic acid, produced by Photorhabdus luminescens, a potential biopesticide against pecan scab. J. Pest Sci., 87, 155-162.

Bonta, R. K. (2017). Application of HPLC and ESI-MS techniques in the analysis of phenolic acids and flavonoids from      green leafy vegetables (GLVs). J. Pharm. Anal., 7, 349-364.

Brar, S. K., Verma, M., Tyagi, R.D., Valero, J.R. (2006). Recent advances in downstream processing and formulation of      Bacillus thurigiensis  based biopesticides. Process Biochem., 41, 323-342.

Bromilow, R. H. (2003). Paraquat and sustainable agriculture. Pest Manag. Sci, 60, 340–349.

Burr, S.A. (2014). DDT (Dichlorodiphenyltrichloroethane). Encyclopedia of Toxicology (Third Edition), 1141-1143.

Calumpang, S. M. F. and Ohsawa, K.(2015). Repellency of marigold, Tagetes erecta volatile organic chemicals to eggplant fruit and shoot borer, Leucinodes orbonalis Guenee. J. Int. Soc. Southeast Asian Agric. Sci., 21, 119-128.

Chen, Y., Li, J., Li, S. X., Zhao, J., Bernier, U. R., Becnel, J. J., Agramonte, N. M., Duke, S. O., Cantrell, C. L. and Wedge,           D. E. (2016). Identification and characterization of biopesticide from Acorus tatarinowii and A. calamus.    Medicinal and Aromatic Crops: Production, Phytochemistry, and Utilization, 1218, 121-143.

Chengala, L. and Singh, N. (2017). Botanical pesticides – a major alternative to chemical pesticides: A review. Int. J. Life        Sci., 5, 722-729.

Chiasson, H.,  Belanger, A., Bostanian, N., Vincent, C. and Poliquin, A. (2001).Acaricidal properties of Artemisia         absinthium and Tanacetum vulgare Essential oil Obtained by Three method of Extraction. J. Econ. Entomo., 94,          167-171.

Coloma, A. G., Martin, L., Mainar, A.M., Urieta, J.S., Fraga, B.M., Rodriguez, V., Vallejo,  Diaz, C.E. (2012). Supercritical         extraction and supercritical anti solvent fractionation of natural products from plant material :Comparative results    on Persea indica . Phytochem Rev, 11, 433-446.

Copping, L. G. and Menn, J. J. (2000). Biopesticides: a review of their action, application and efficacy. Pest  manag. Sci.,      56, 651-676.

Dashtbazorg, S. S., Miao, S. and Ju, L. K. (2015). Rhamnolipids as Environmentally Friendly Biopesticide Against Plant      Pathogen Phytophthora sojae. J. Am. Inst. Chem. Eng., 35.

Decool, G., Kfoury, M., Paitel, L., Sardo, A., Fourmentin, S. (2024). Cyclodextrins as molecular carriers for biopesticides: a review. Environ. Chem. Lett., 22, 321–353.

Deota, P. T., Upadhyay, P. R., Patel, K.B., Mehta, K. J., Mehta, M. H. (2000). Estimation and isolation of Azadirachtin-A      from Neem seed kernels using High performance liquid chromatography. J. Liq. Chromatogr. Relat. Technol., 23,          2225-2235.

Devi, S. S. and Rao, K.V. B. (2017). Exploration of antimicrobial compounds from streptomyces S9 against a         phytopathogen, Corynespora cassiicola. J.  Biopest., 10, 1-9.

Dhouib, I., Jallouli, M., Annabi, A., Marzouki, S., Gharbi, N., Elfazaa, S.,  Lasram, M. M. (2016).  From immunotoxicity to    carcinogenicity: the effects of carbamate pesticides on the immune system. Environ Sci. Pollut Res, 23, 9448– 9458.

Diaz, G. E., Jimenez, J. A. V., Collado, J. L. And Lagunes, D. A. R. (2010). Azadirachtin Extraction Using Cold Press and Soxhlet Methods.  Biopestic. Int., 6, 45–51.

Djamann, A., Agustien, A., Zam, S. I., Jannah, M., Lalfari, R. S., Aldi, Y., Dewi, A. P., and Suci, R. P. (2018).   Characterization of biopesticide compounds from Bacillus subtilis AAF2 UAAC 20701    fermentation product. Int. Res. J. Pharm., 9.

Dogara, A. M., Hamad, S. W., Halliru, B. S., Wada, N., and Dalorima, T. (2022). Influences of different concentrations of          herbicides on the growth and yield of maize as well as their effects on the associated weeds in North-Western    Nigeria. Passer J. Basic Appl. Sci. 4, 31–36.

Drumea, V., Dumitriu, B., Voinicu, I. B., Olariu, L. (2022). Study on Thiophenes Extraction Efficacy from Tagetes patula           L.. Acad. Roman. Sci. Annals – Ser. Biol. Sci., 11.

Eskilsson, C. S., Bjorklund, E. (2000) Analytical scale Microwave assisted  extraction. J. Chromatogr. A, 902, 227-250.

Farooq, M. A., Arif, M. J., Gogi, M. D., Nawaz, A., and Atta, B. (2019). Comparative efficacy of different pesticide residue   mitigation modules in mango. Am. J. Biomed. Sci. Res. 4, 214–219.

Fathi, R. M., Fauzantoro, A., Rahman, S. F., Gozan, M. (2018). Column Chromatography Isolation of Nicotine from     Tobacco Leaf Extract (Nicotiana tabaccum L.). AIP Conf. Proc., 1933, 030011.

Fojtová, J., Lojková, L., Kubáň, V. (2010). Supercritical fluid extraction as a tool for isolation of monoterpenes from             coniferous needles and walnut-tree leaves. Cent. Eur. J. Chem., 8, 409–418.

Gallo, M., Formato, A., Ianniello, D., Andolfi, A., Conte, E., Ciaravolo, M., Varchetta, V., Naviglio, D. (2017). Supercritical   fluid extraction of pyrethrins from pyrethrum flowers(Chrysanthemum cinerariifolium) compared to traditional    maceration and cyclic pressurization extraction. J. Supercrit. Fluids, 119, 104–112.

Garces, A., Pires, I., and Rodrigues, P. (2020). Teratological effects of pesticides in vertebrates: a review. J. Environ. Sci.   Health A, 55, 75–89.

Garcia, A. P., Romero D., and Vicente, A. D. (2011). Plant protection and growth stimulation by micro organisms:           biotechnological application of Bacilli in agriculture. Curr. Opin. Biotechnol., 22, 187-193.

Gasic, S. and Tanovic, B. (2013). Biopesticide formulation, possibility of application and future trends. Pestic. Phytomed.(    Belgrade), 28, 97-102.

Gomathi, D. & Kalaiselvi, M. & Ravikumar, G. & Devaki, K, and Uma, C. (2015). GC-MS analysis of bioactive compounds    from the whole plant ethanolic extract of Evolvulus alsinoides (L.) L. J Food Sci. Technol., 52, 1212–1217.

Govindarasu, R., Baskaran, D., Vignesh, P., Nannapuraju, P. S. R. (2024).  Intensified extraction of geraniol from palmarosa leaves using diverse hydrotrope‑assisted extraction techniques. Biomass Conv. Bioref. 14, 10585–10598.

Grimalt, S., Thompson, D. G., Coppens, M., Chartrand, D. T., Shorney, T., Meating, J. and Scarr, T. (2011). Analytical            study of Azadirachtin and 3- Tigloylazadirachtol residues in foliage and phloem of Hardwood  tree species by    liquid chromatography-electrospray Mass spectrometry. J. Agric. food Chem., 59, 8070-8077.

Gupta, R. C., Malik, J. K.,  Milatovic, D. (2011). Organophosphate and Carbamate Pesticides. Reprod. Develop. Toxicol., 471-486.

Hamimi, S. A., Mayoral, A. A., Cunico, L. P. and Turner, C. (2016). Carbon Dioxide Expanded Ethanol Extraction:   Solubility and Extraction Kinetics of αPinene and cis-Verbenol. Anal. Chem., 88, 43364345.

HanW., TianY.,  Shen, X.  (2018). Human exposure to neonicotinoid insecticides and the evaluation of their potential      toxicity: An overview. Chemosphere,  192, 59-65.

Jacob, J. W., Cheseto, X., Habtemariam, S. and Torto, B. (2017). Mosquito larvicidial activity of Cassia tora seed extract       and its key anthraquinones aurantio-obtusin and obtusin. Journal of Parasit. Vectors, 10:562.

Jadeja, G.C., Maheshwari, R.C., Naik, S.N. (2011).  Extraction of natural insecticide azadirachtin from neem (Azadirachta   indica A. Juss) seed kernels using pressurized hot solvent. J. Supercrit. Fluids, 56, 253–258.

Jayaraj, R., Megha, P., Sreedev, P. (2016). Organochlorine pesticides, their toxic effects on living organisms and their fate in     the environment. Interdiscip. Toxicol., 9, 90–100.

Jefferies, P. R., Toia, R. F., Brannigan, B., Pessah, I. and Casida'J, J. E. (1992). Ryania Insecticide: Analysis and Biological     Activity of 10 Natural Ryanoids. J. Agric. Food Chem. 40, 142-146.

JhaA. K.,  Sit, N. (2022). Extraction of bioactive compounds from plant materials using combination of various novel      methods: A review. Trends Food Sci. Technol., 119,  579-591.

Jime´nez, J. J., Bernal, J.L., Nozal, M.J. d., Novo, M., Higes, M., Llorente, J. (2000).  Determination of rotenone residues in raw honey by solid-phase extraction and high-performance liquid chromatography. J. Chromatogr. A, 871, 67–73.

Johnson, S. and Morgan, E. D. (1997).Super critical fluid extraction of oil and  triterpenoids from neem seeds. Phytochem.      Anal. 8, 228-232.

Just, J., Bunton, G. L., Deans, B. J., Murray, N. L., Bissember, A. C., and Smith, J. A.(2016). Extraction of Eugenol from Cloves Using an Unmodified Household Espresso Machine: An Alternative to Traditional Steam-Distillation. J. Chem. Educ., 93, 213-216.

Kabir, K. E., Choudhary, M. I., Ahmed, S., Tariq, R. M. (2013). Growth-disrupting larvicidal and neurobehavioral toxicity             effects of seed extrct of Seseli diffusum against Aedes aegypti. Ecotoxicol. Environ. Saf., 9052-60.

Kagan, I.A., Flythe, M.D. (2014).Thin-layer Chromatographic (TLC) Separations and Bioassays of Plant Extracts to Identify Antimicrobial Compounds. J. Vis. Exp., 85, e51411.

Karthika, K. And Paulsamy, S. (2015). TLC and HPTLC Fingerprints of Various Secondary Metabolites in the Stem of the         Traditional Medicinal Climber, Solena amplexicaulis. Indian J. Pharm. Sci., 77, 111-116.

Kheawfu, K., Kaewpinta, A., Chanmahasathien, W., Rachtanapun, P. and Jantrawut, P. (2021). Extraction of Nicotine from      Tobacco Leaves and Development of Fast Dissolving Nicotine Extract Film. Membranes, 11, 403.

Kim, K. H., Kabir, E., Jahan, S. A. (2017). Exposure to pesticides and the associated human health effects. Sci. Total            Environ., 575, 525–535.

Konappa, N.,  Udayashankar, A. C.,  Krishnamurthy, S.,  Pradeep, C. K.,  Chowdappa, S.  & Jogaiah, S.  (2020). GC–MS           analysis of phytoconstituents from Amomum nilgiricum and molecular docking interactions of bioactive server         ogenin acetate with target proteins. Sci. Rep., 10, 16438. 

Kousar, M. U., Jabeen, A., Fatima, T., Hussain, S. Z., Zargar, I. A., Amin, T., Yaseen, M. (2023).  Optimization of      ultrasonic-assisted extraction of eugenol-rich fraction from basil leaves: Characterization of extract for phenols,     flavonoids and antioxidant activity. Food Chem. Adv., 3, 100374.

Kuganathan, N. and Ganeshalingam, S. (2011). Chemical analysis of Datura metel leaves and investigation of the Acute    toxicity on Grasshoppers and red ants. E-J. Chem.,8, 107-112.

Kumar, J., Ramlal, A., Mallick, D. and Mishra, V. (2021). An Overview of Some Biopesticides and Their Importance in Plant Protection for Commercial Acceptance.  Plants, 10, 1185.

Kumar, M. and Ramsingh. (2002). Potential of Pongamia glabra vent as an insecticide of plant origin. Biol. Agric. Hortic.,      20, 29-50.

Kumar, S. and Singh, A. (2015). Biopesticides: Present Status and the Future Prospects. J. Biofertil. Biopestici., 6, e129.

Kumawat, N., Shekhawat, P. S., Kumar, R. and Sanwal, R.C. (2014). Formulation of Biopesticides for Insect Pests and         Diseases Management in organic Farming. Pop. Kheti, 2, 237-242.

Lautie, E., Rasse, C., Rozet, E., Mourgues, C., Vanhelleputte, J. P., Leclercq, J.Q. (2013). Fast microwave-assisted           extraction of rotenone for its quantification in seeds of yam bean (Pachyrhizus sp.).  J. Sep. Sci., 36, 758–763.

Liauw, M. Y., Natan, F.A., Widiyanti, P., Iksari, D., Indraswati, N. and Soetaredjo, F.E.(2008). Extraction of neem oil        (Azadirachta indica ) using N-Hexane and Ethanol; Studies of oil quality , kinetic and Thermodynamic. ARPN       J. Eng. Appl. Sci., 3.

Liu, X. C., Cheng, J., Zhao, N. N. and Liu, Z. L. (2014). Insecticidal Activity of Essential Oil of Cinnamomum cassia and its    Main Constituent, trans-Cinnamaldehyde, against the Booklice, Liposcelis bostrychophila. Trop. J. Pharm. Res.,       13, 1697.

Liu, X. H.,  Wang, Q.,  Sun, Z. H.,  Wedge, D. E.,  Becnel, J. J.,  Estep, A. S.,  Tan, C. X.,  Weng, J. Q.  (2017). Synthesis       and insecticidal activity of novel pyrimidine derivatives containing urea pharmacophore against Aedes aegypti.    Pest Manag. Sci., 73, 953-959.

Lokanadhan, S., Muthukrishnan, P. and Jeyaraman, S. (2012). Neem products and their agriculture application. J. Biopest.,       5, 72-76.

Machado, M., Dinis, A.M., Santos-Rosa, M., Alves, V., Salgueiro, L., Cavaleiro, C., Sousa, M.C. (2013). Activity of            Thymus capitellatus volatile extract, 1,8-cineole and borneol against Leishmania species. Vet. Parasitol., 200, 39-       49.

Mahrous, E. A.,  Farag, M. A.,  (2015). Two dimensional NMR spectroscopic approaches for exploring plant metabolome: A            review. J. Adv. Res., 6,  3-15.

Maya, C., Mantell, C., Ossa, E. J. M.D. L. and Casas, L. (2022). Supercritical Extraction of a Natural Pyrethrin-Rich Extract      from Chrysanthemum Cinerariifolium Flowers to Be Impregnated into Polypropylene Films Intended for     Agriculture Applications. Applied Chem, 2, 106–116.

Mbatchou, V. C., Dickson, R. A., Amponsah, I. K., Mensah, A. Y., Habtemariam, S. (2018). Protection effect of the anthraquinone, cassiatorin and aurantio-obtusin from seeds of Senna tora against cowpea weevil attack. Asian            Pac. J. Trop. Biomed., 8, 98-105.

Mbatchou, V. C., Tchouassi, D. P., Dickson, R. A., Annan, K., Mensah, A. Y., Amponsah, I. K., Khanam, Z., Yousef, H. M. A., Singh, O. and Bhat, I. U. H. (2017). NEEM oil. Green Pesticides Handbook.

Mossa, A.T. H. (2016). Green pesticides :Essential oils as biopesticides in insect-pest management. J. Environ. Sci.    Technol., 9, 354-378.

Mostafa, M., Hossain, H., Hossain, M. A., Biswas, P. K., Haque, M. Z. (2012) Insecticidal activity of plant extracts against    Tribolium castaneum herbst . J.  Adv. Sci. Res., 3, 80-84.

Naboulsi, I., Aboulmouhajir, A., Kousni, L., Bekkaoui, F., Yasri, A. (2018). Plant extract and secondary metabolites, their           extraction method and use agriculture for controlling crop stresses and improving productivity: A Review.    Acad.  J. Med. Plants, 6, 223-240.

Naniwadekar, M.Y., Jadhav, A.S. (2012). Process development of pesticide production from Azadirachta indica A. Juss.          Int. J. Agric. Innov.  Res., 1.

Nawaz, M., Mabubu, J. I., Hua, H. (2016). Current and advancement of biopesticides : Microbial and Botanical pesticides.      J. Entomol.  Zool. Stud., 4, 241-246.

Nebapure, S. M., Srivastava, C. and Walia, S. (2017). Insecticidal and repellency potential of Glory lily, Gloriosa superb            extracts against red rust flour beetle Tribolium castaneum. Indian J. Entomol., 79, 474-478.

Nicoletti, M., Maccioni, O., Coccioletti, T., Mariani, S. and Vitali, F. (2012). Neem tree( Azadichta indica) as source of      biopesticides. Insecticides- Advances in Integrated pest management, 1-20.

Nikolaivits, E., Agrafiotis, A., Baira, E., Goff, G. L., Tsafantakis, N., Chavanich, S. A., Benayahu, Y., Ouazzani, J.,      Fokialakis, N. and Topakas, E. (2020). Degradation Mechanism of 2,4-Dichlorophenol by Fungi Isolated from    Marine Invertebrates. Int. J. Mol. Sci., 21, 3317.

Ore, O. T.,   Adeola , A. O.,   Bayode,  A. A., Adedipe,  D. T., Nomngongo, P. N.  (2023). Organophosphate pesticide             residues in environmental and biological matrices: Occurrence, distribution and potential remedial approaches.    Environ. Chem.  Ecotoxicol., 5,  9-23.

Papa, G., Kirby, J., Konda, N. V. S. N., Tran, M. K., Singh, S., Keasling, J. D., Peterg, G.F. and Simmons, B. A. (2016).          Development of an integrated approach for α-pinene recovery and sugar production from loblolly pine using ionic    liquids. Green Chem., 19, 1117-1127.

Pathak, V. M., Verma, V. K., Rawat, B. S., Kaur, B., Babu, N. Sharma, A., Dewali, S., Yadav, M., Kumari, R., Singh, S.,         Mohapatra, A., Pandey, V., Rana, N. and Cunill, J. M. (2022) Current status of pesticide effects on environment,    human health and it’s eco-friendly management as bioremediation: A comprehensive review. Front. Microbiol.,        13, 962619.

Payra, S. K., Goswami, D., Pan, S., Bera, A., Jana, S., Sing, J., Bhowmik, A. (2023). Review on Effects of Organophosphate            Pesticides in Human Health and Way to Mitigates its Harmful Impacts. Int. J. Multidiscip. Res. Ana., 6,  5594-   5599.

Perich, M. J., Wells, C., Bertsch, W. and Tredway, K. E. (1995). Isolation of the Insecticidal components of Tagetes minuta      (Compositae) against Mosquito Larvae and Adults. J. Am. Mosq. Control Assoc., 11, 307-310.

Praveen, U. S., Gowtham, M. D., Gowda, C. V. Y., Nayak, V. G., Mohan, B. M. (2012). Detection of residues of Cardelides      of Nerium oleander by HPTLC in autopsy samples. Int. J.  Med. Toxicol.  Forensic Med., 2, 135-142.

Prestes, O. D., Antonio, J., Sanchez, P., Gonzalez, R. R., Grio, S. L., Frenich, A. G., Vidal, J. L. M. (2012). Comparision of             several extraction procedures for the determination of biopesticides in soil samples by ultrahigh pressure    LCMS/MS. J. Sep. Sci., 35, 861-868.

Puri, M., Sharma, D. and Barrow, C. J. (2012). Enzyme-assisted extraction of bioactives from plants. Trends in   Biotechnol., 30, 37-44.

Pyne, S. and Paria, K. (2022). Optimization of extraction process parameters of caffeic acid from microalgae by supercritical   carbon dioxide green technology. BMC Chem., 16:31.

Rakhimol, K., Thomas, S., Volova, T., and Jayachandran, K. (2020). Controlled Release of Pesticides for Sustainable    Agriculture. New York, NY: Springer.

Rani, L.  Thapa, K., Kanojia,  N., SharmaN., Singh, S.,  Grewal , A. S., Srivastav ,  A. L., Kaushal, J.  (2021).. An extensive    review on the consequences of chemical pesticides on human health and environment. Journal of Clean.          Prod., 283, 124657.

Rodgers, P. B. (1993). Potential of biopesticide in agriculture. Pestic. Sci., 39, 117-129.

Santos, A. L., Chierice, G. O., Alexander, K. S., Riga, A., Matthews, E. (2009). Characterization of the raw essential oil           eugenol extracted from Syzygium aromaticum L. J. Therm. Anal. Calorim., 96, 821–825.

Saxena, H.O., Tripathi, Y.C., Pawar, G., Kakkar, A., Mohammad, N. (2014). Botanicals as Biopesticides : Active chemical        constituents and biocidal action. Familiarizing with local biodiversity, (pp.227 - 246).

Sathiyamoorthy, P., Shanmugasundaram, S. (1996). Preparation of Cyanobacterial Peptide Toxin as a Biopesticide against            cotton pest. Appl. Microbiol. Biotechnol., 46, 511-513.

Savant, S. K. (1999). Simple method for enrichment of Azadirachtin from Neem seeds. J. Sci.  Ind.         Res., 58, 990-994.

Seiber, J. N., Coats, J., Duke, S. O. and  Gross, A. D. (2014). Biopesticides: States of the art and future opportunities.            J.         Agri. Food Chem., 62, 11613-11619.

Semren, T. Ž., Žunec, S. and Pizent, A. (2018). Oxidative stress in triazine pesticide toxicity: a review of the main biomarker          findings. Arh. Hig. Rada. Toksikol., 69,109-125.

Sharma, A. and Gupta, R. (2009).Biological activity of some plant extract against Pieris brassicae. J. Biopest., 2, 26-31.

Sharma, N. and Singhvi, R. (2017). Effects of Chemical Fertilizers and Pesticides on Human Health and Environment: A      Review. Int. J. Agric. Environ. Biotechnol., 10, 675-679.

Shrivastava, N., Chauhan, A. S. and Sharma, B. (2012).Isolation and characterization of some phytochemicals from Indian    traditional plants. Biotechnol. Res. Int., volume 2012.

SilvaL.C. D., SouzaM. C.,  SumereB. R.,  SilvaL.G.S.,  CunhaD.T. D., BarberoG. F.,  BezerraR. M.N.,  Rostagno, M. A. . (2020). Simultaneous extraction and separation of bioactive compounds from apple pomace using    pressurized liquids coupled on-line with solid-phase extraction. Food Chem., 318, 126450.

Singh, G., Singh, O. P., Lampasona, M.P.D.,  and Catalan, C. A.N. (2003). Studies on essential oils. Part 35: chemical and      biocidal investigation on Tagetes erecta leaf volatile oil. Flavour Fragr. J.,18, 62-65.

Singh, Z., Kaur, J., Kaur, R., Hundal, S. S. (2016). Toxic Effects of Organochlorine Pesticides: A Review. Am. J.    BioSci., 4, 11-18.

Sinha, S., Murthy, P.S.N., Rao, C.V.N., Ramprasad, G., Sitaramainh, S., Kumar, D.G. and Stamati, P. N., Maipas, S., Kotampasi, C., Stamatis, P. and Hens, L. (2016). Chemical Pesticides and Human Health: The Urgent Need for a         New Concept in Agriculture. Front. Public Health, 4, 148.

Song, L., Wang, J., Gao, Q., Ma, X., Wang, Y., Zhang, Y., Xun, H., Yao, X. and Tang, F. (2018). Simultaneous            determination of fiveazadirachtins in the seed and leaf extracts of Azadirachta indica by automated         onlinesolid‑phase extraction coupled with LC–Q‑TOF–MS. Chem. Cent. J., 12, 1-9.

Soni, H., Mishra, K.,  Sharma, S. & Singhai, A. K. (2012). Characterization of Azadirachtin from ethanolic extract of leaves   of Azadirachta indica. J. Pharm. Res., 5, 199-201.

Tajane, S., Dadhe, P., Mehetre, S. and Mandavgane, S. (2017). Characterization and testing of fine powder formulation of   whole neem fruits. Current Sci., 112.

Tang, W., WangD.,  WangJ.,  WuZ.,  LiL.,  HuangM.,  XuS.,  Yan, D.  (2018). Pyrethroid pesticide residues in the       global environment: An overview. Chemosphere, 191, 990-1007.

Tatke, P. and Jaiswal, Y. (2011). An overview of Microwave Assisted Extracted and its Application in Herbal Drug Research. Res.  J. Med. Plant, 5, 21-31.

Teixeira, L. A.,  Andaloro, J. T.  (2013). Diamide insecticides: Global efforts to address insect resistance stewardship     challenges. Pestic. Biochem. Phys., 106, 76-78.

Thakker, M. R., Parikh, J. K. and Desai, M. A. (2018). Ultrasound Assisted Hydrotropic Extraction: A Greener Approach for     the Isolation of Geraniol from the Leaves of Cymbopogon martini. ACS Sustainable Chem. Eng., 6, 3215-3224. 

Thakur, D.R. and Devi, B. (2016). Biopesticidal efficacy of Berberis lyceum Linnaeus and Cannabis sativa Linnaeus against Callosobruchus chinensis Linnaeus ( Coleoptera : Bruchidae). J. Insect Sci., 29, 227-232.

Thomson, M. and Vijan, A. (2016). Environmental Friendly Bio-pesticides : A Review. Research and Reviews. J.          Agric.  Allied Sci., 5, 31-39.

Troczka, B. J.,  Williamson, M. S.,  Field, L. M., and Davies, T. G. E.  (2017). Rapid selection for resistance to diamide         insecticides in Plutella xylostella via specific amino acid polymorphisms in the ryanodine receptor.     Neurotoxicol.,             60, 224–233.

Tsai, Y. L., Chiou, S. Y., Chan, K.C., Sung, J. M., Lin, S. D. (2012). Caffeic acid derivatives, total phenols, antioxidant and        antimutagenic activities of Echinacea purpurea flower extracts. LWT - Food Sci. Technol., 46, 169e176.

Ullah, M. R., and Dijkstra, F. A. (2019). Fungicide and bactericide effects on carbon and nitrogen cycling in soils: a meta-   analysis. Soil Syst., 23.

Vera, J., Sa, L. C.,  Paiga, P., Braganza, I., Fernandes, V. C., Domingues, V. F., Matos, C. D. (2013). QuChERS and soil          analysis. Sam. Pre., 54-17.

Villaverde, J. J., Espana, P. S., Moran, B. S., Goti, C. L. and Prados, J. L. A. (2016). Biopesticides from natural products;     Current Development ,Legislative Framework and Future Trends.  BioResour., 11, 5618-5640.

Walch, S. G., Kuballa, T., Stühlinger, W. and Lachenmeier, D. W. (2011). Determination of the biologically active flavor            substances thujone and camphor in foods and medicines containing sage (Salvia officinalis L.). Chem. Cent.      J., 5,    44.

Wany, A., Kumar, A., Nallapeta, S., Jha, S., Nigam, V. K., Pandey, D. M. (2014).  Extraction and characterization of         essential oil components based on geraniol and citronellol from Java citronella (Cymbopogon winterianus Jowitt)    Plant Growth. Regul., 73, 133–145.

Wardatun,  S., Rustiani, E., Alfiani, N., Rissani, D. (2017). Study Effect Type of Extraction Method And Type of Solvent To     Cinnamaldehyde and Trans-Cinnamic Acid Dry Extract Cinnamon (Cinnamomum burmanii [Nees & T, Nees]    Blume).  J. Young Pharm., 9, 49-51.

Wongsa, P., Phatikulrungsun, P. & Prathumthong, S. (2022). FT-IR characteristics, phenolic profiles and inhibitory potential         against digestive enzymes of 25 herbal infusions. Sci. Rep., 12, 6631.

Wrona, O., Rafińska, K., Możeński, C., Buszewski, B. (2017). Supercritical Fluid Extraction of Bioactive Compounds from        Plant Materials. J. AOAC Int., 100, 1624–1635.

Wu, H., Hendrawinata, W., Yu, Y., Gao, X., Li, Y., Bartle, J. and Grayling, P. (2011). Effect of Hydrodistillation on 1,8-        Cineole Extraction from Mallee Leaf and the Fuel Properties of Spent Biomass. Ind. Eng. Chem. Res., 50, 11280–   11287.

Xia, E. Q., Li, H. L., Xu, X. R., Li, F., Deng, G. F., Li, S., Wu, S. and Li, H. B. (2012). Ultra sound assisted extraction of         Oxymatrine from Sophora flavescens. J. Med. Plant Res., 6, 1991-1996.

Ye, J. C., Hsiao, M. W., Hsieh, C. H., Wu, W. C., Hung, Y. C., Chang, W. C. (2010). Analysis of Caffeic acid Extaction        from Ocimum gratissimum Linn. By High performance Liquid Chromatography and its Effects on a Cervical     Cancer Cell Line. Taiwan J. Obstet. Gynecol., 49, 266-271.

Yun, A. S., Ovatlarnporn, C., Itharat, A., Wiwattanapatapee, R. (2006). Extraction of rotenone from Derris elliptica and        Derris malaccensis by pressurized liquid extraction compared with maceration. J. Chromatogr. A, 11, 172-176.             

Zahari, R., Halimoon, N., Ahmad, M.F. and Ling, S.K. (2018). Antifungal compound isolated from Catharanthus roseus       L.(pink) for biological control of root rot rubber diseases. Int. J.  Anal. Chem., 2018, 8150610.

Zavoi, S., Fetea, F., Ranga, F., Pop, R. M., Baciu, A., Socaciu, C. (2011). Comparative Fingerprint and Extraction Yield of      Medicinal Herb Phenolics with Hepatoprotective Potential, as Determined by UV-Vis and FT-          MIR.    Spectroscop. Not. Bot. Horti. Agrobo., 39, 82-89.

Zhan, J., Liang, Y., Liu, D., Ma, X., Li, P., Liu, C., Liu, X., Wang, P. and Zhou, Z. (2018).  Antibiotics may increase triazine        herbicide exposure risk via disturbing gut microbiota. Microbiome, 6, 224.

Zheng, F., Xie, Q., Ren, Q., and Kong, J.  (2024). Extraction and Purification of Nicotine from Tobacco Rhizomes by    Supercritical CO2.  Molecules,  29, 1147.

Zubairi, S. I., Sarmidi, M. R. & Aziz, R. A. (2015). A Thermal Degradation (Thermolysis) Study of Rotenone         Extracted from Derris elliptica Roots Using Reverse-Phase High Performance Liquid Chromatography (RP-   HPLC). Sains Malays., 44, 121–126.

Related Images:

Recent Images

Herbal Alternatives for Oral Health:  Mechanistic Exploration with their Market Potential
A Review on Extraction, Identification and Application of Pesticidal Active Phytoderived Metabolites
Determination of Total Dissolved Solids (TDS) of RO Purified Drinking Water Samples in Raipur
Time of the Day Variability in Pit-Building Behavior of Antlion Larvae
A Comprehensive Review of a particular Skin Injury: Pathogenesis, triggers, and current Treatment Options
Enhanced antioxidant activity in Curcuma caesia Roxb. microrhizomes treated with silver nanoparticles
Studies on the Interaction of Imidazolium Ionic Liquids with Human Serum Albumin
Basic and Advanced Logical Concept Derived from Surface Enhanced Infrared Spectroscopy (SEIRS) as Sensing Probe for Analysis of Chemical Species: A Brief Review
Soil Erosion Risk Estimation by using Semi Empirical RUSLE model: A case study of Maniyari Basin, Chhattisgarh
An Estimator of Population Variance Using Multi-Auxiliary Information


Recomonded Articles:

Author(s): Suman Shrivastava, Pooja Deshpande, S. J. Daharwal*

DOI: 10.52228/JRUB.2018-31-1-6         Access: Open Access Read More

Author(s): Swati Jain; Somesh Kumar Dewangan

DOI: 10.52228/JRUB.2021-34-1-9         Access: Open Access Read More

Author(s): Pooja Deshpande, Suman Shrivastava, S.J. Daharwal*

DOI: 10.52228/JRUB.2018-31-1-7         Access: Open Access Read More

Author(s): Monika Swami; Kinjal Patel

DOI: 10.52228/JRUB.2021-34-1-2         Access: Open Access Read More

Author(s): Surendra G Gattani; Ravina Shete; Sandeep Ambore

DOI:         Access: Open Access Read More

Author(s): Anil Kumar Verma*; Swati Sahu; Mohan Patel; Sanjay Tiwari

DOI: 10.52228/JRUB.2020-33-1-5         Access: Open Access Read More

Author(s): Rajesh Shukla; Neetu Harmukh; Nayan Kumar Pandey

DOI:         Access: Open Access Read More

Author(s): Nikita Verma; Swarnlata Saraf

DOI:         Access: Open Access Read More

Author(s): Taranjeet Kukreja; Swarnlata Saraf

DOI: 10.52228/JRUB.2023-35-2-5         Access: Open Access Read More

Author(s): AR Sood and RC Rathor

DOI:         Access: Open Access Read More

Author(s): Subhendu Saha

DOI:         Access: Open Access Read More

Author(s): Dinesh Kumar Sharma; Bhabani S Nayak

DOI:         Access: Open Access Read More