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Author(s): Taranjeet Kukreja, Swarnlata Saraf

Email(s): swarnlatasaraf@gmail.com

Address: University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur - 492010, Chhattisgarh, India.
University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur - 492010, Chhattisgarh, India.
*Corresponding Author: swarnlatasaraf@gmail.com

Published In:   Volume - 35,      Issue - 2,     Year - 2022

DOI: 10.52228/JRUB.2023-35-2-5  

ABSTRACT:
Itraconazole is a triazole antifungal agent that is synthesised. Itraconazole has been manufactured into a variety of pharmacological formulations and administered in a variety of ways. Itraconazole pills are used to treat pulmonary fungi that can cause fungal infection and spread throughout the body. Because Itraconazole is not yet officially listed in any pharmacopoeia, only a few procedures for quality control and stability testing in pharmaceutical formulations have been published. The goal of this study is to develop a more precise, easy, and cost-effective spectrophotometric approach for analysing Itraconazole in bulk and capsule dosage forms with improved precision, accuracy, and sensitivity. The UV spectroscopic determination was performed with Chloroform as the solvent at an absorption maximum of 267 nm. Linearity over the concentration range in the UV spectroscopic approach. The linearity of Itraconazole over the concentration range was found to be 1-10 g/ml using the UV spectroscopic technique, with a correlation coefficient of 0.999. The findings of the analyses were statistically and the recovery studies have confirmed this.

Cite this article:
Kukreja and Saraf (2022). UV Spectroscopy Analysis for Itraconazole . Journal of Ravishankar University (Part-B: Science), 35(2), pp. 62-67.DOI: https://doi.org/10.52228/JRUB.2023-35-2-5


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