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Author(s): Shraddha Chauhan, Lata Sheo Bachan Upadhyay*

Email(s): contactlataupadhyay@gmail.com

Address: National Institute of Technology Raipur, Department of Biotechnology, Raipur, Chhattisgarh, 492010
*Corresponding author: contactlataupadhyay@gmail.com

Published In:   Volume - 32,      Issue - 1,     Year - 2019

DOI: 10.52228/JRUB.2019-32-1-5  

Ground water arsenic contamination is one of the major global issues in recent days. The long exposure of arsenic can cause hazardous health effects like skin cancer, lung cancer as well as heart diseases. Conventional methods for monitoring arsenic level is often strenuous and require highly skilled personals to perform the measurements, thus there is a need to develop a simple and cost- effective techniques for quick and continuous monitoring. Paper-based approach for detecting the arsenic is a low-cost, non-instrumental method and provides on-site detection of water contaminants. In this study a rapid, simple and affordable method for arsenic detection was developed. This methodology involves the generation of arsine gas inside the analysis system that reacts with the silver nitrate present on the paper analytical device (PAD). This reaction between silver nitrate and arsine gives a colored product that was detected by scanning the colored intensity with image processing software. The iron oxide nanoparticles act as a reducing agent that causes the generation of arsine gas from arsenic. These nanoparticles were synthesized through green technology by using henna extract. The whole reaction takes place in the glass vial with the rubber cap on it at which the PAD was placed. Experimental parameters like concentration of reducing agent, silver nitrate and reaction time were evaluated that affects the performance of the analytical process. Under optimal conditions the method showed the detection limit of 0.005ppm.

Cite this article:
Chauhan and Upadhyay (2019). Development and fabrication of a paper based analytical device using iron oxide nanoparticles to detect arsenic in aqueous samples. Journal of Ravishankar University (Part-B: Science), 32 (1), pp. 23-26.DOI: https://doi.org/10.52228/JRUB.2019-32-1-5


Chauhan, S. and Upadhyay, L.S.B. (2018). An efficient protocol to use iron oxide nanoparticles in microfluidic paper device for arsenic detection. MethodsX, 5: 1528-1533.

Chowdury,M.A., Walji, N., Mahmud, M.A. and MacDonald, B.D. (2017). Paper based Microfluidic Device with a Gold Nanosensor to Detect Arsenic Contamination of  Groundwater  in  Bangladesh. Micromachines, 8: 71.

Nie,J., Zhang, Y., Lin, L. Li, C., Zhou, S., Zhang, L. and Li, J. (2012). Low-cost fabrication of paper-based microfluidic devices by one-step plotting. Anal. Chem. 84: 6331-6335.

Saif,S., Tahir, A. and Chen, Y. (2016). Green synthesis of iron nanoparticles and their environmental applications and implications. Nanomaterials,6:209.

Smith, A.H., Lingas E.O., and Rahman, M. (2000). Contamination of drinking-water by arsenic in Bangladesh: a public healthemergency. Bulletin of the World Health Organization 78: 1093- 1103.

Stocker,J., Balluch, D., Gsell, M., Harms, H., Feliciano, J., Daunert, S., Malik, K.A. and Van der Meer, J.R. (2003). Development of a set of simple bacterial biosensors for quantitative and rapid measurements of arsenite and arsenate in potable water,Environ. Sci. Technol. 37:4743- 4750.

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