Abstract View

Author(s): Suchitraku Panigrahy, Renu Bhatt

Email(s): panigrahysuchitra@gmail.com

Address: Department of Biotechnology, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur 495 009, India.

Published In:   Volume - 29,      Issue - 1,     Year - 2016

DOI: Not Available

ABSTRACT:
Diabetes is a chronic metabolic disease associated with severe complications. Despite of progress in medicinal industry herbal medicines are preferred due to their reducing side effects. Hedychiumcoronarium member of zingiberaceae family has been reported as a medicine for various diseases. The present study was undertaken to isolate and characterize the compounds from the extract of rhizome of H.coronarium and to evaluate their efficacy on in-vitro models of type-Il diabetes. Isolation of compounds from the active dichloromethane (DCM) and ethyl acetate (EA) extract of rhizome of H.coronarium was achieved by Silica gel column chromatography to yield different fractions. The bioactive fractions were then subjected to further purification to obtain purificd compounds. The antidiabetic properties of the compounds were evaluated in-vitro by a- amylase and a- glucosidase enzyme assay. The isolated terpenes from the fractions exhibited inhibition against a- amylase and a- glucosidase in in-vitro correlating to reduce the plasma glucose level. The present investigation suggests the use of the isolated terpenes for treatment of type-ll diabetes in future to reduce the side effects of marketed drugs.

Cite this article:
Panigrahy and Bhatt (2016). Target Guided Isolation and In-Vitro Antidiabetic Activity of Compounds Isolated from Hedychium coronarium Rhizome. Journal of Ravishankar University (Part-B: Science), 29(1), pp.104-105.


References not available.

Related Images:



Recent Images



Modeling of Abnormal Hysteresis in CsPbBr3 based Perovskite Solar Cells
Impact of Melatonin on Growth and Antioxidant Activity of Cicer arietinum L. Grown under Arsenic Stress
Assessment of Cymoxanil in Soil, Water and Vegetable Samples
Need of Gallium Recovery from Waste Samples: A Review
Higher Order Statistics Based Blind Steg analysis using Deep Learning
Covid-19 related School Closure Impact on School going Children & Adolescents of Raipur, Chhattisgarh
Determination of Pentachlorophenol in Environmental Samples by Spectrophotometry
Simple and Cost Effective Polymer Modified Gold Nanoparticles Based on Colorimetric Determination of L-Cysteine in Food Samples
Investigation on Design and Device Modeling of High Performance CH3NH3PbI3-xClx Perovskite Solar Cells
Remotely Sensed Image Based on Robust Segmentation and GIS System

Tags


Recomonded Articles:

Author(s): Pooja Deshpande, Suman Shrivastava, S.J. Daharwal*

DOI: 10.52228/JRUB.2018-31-1-7         Access: Open Access Read More

Author(s): Subhendu Saha

DOI:         Access: Open Access Read More

Author(s): AR Sood and RC Rathor

DOI:         Access: Open Access Read More

Author(s): Parminder Kaur; GI Mundhara; JS Tiwari; HS Kar

DOI:         Access: Open Access Read More

Author(s): B S Ajitkumar; Prashant S Hande; Vikas Jha; Pratiksha Alagh; Shailendra Rane

DOI:         Access: Open Access Read More

Author(s): Parminder Kaur; G.L. Mundhara; J.S. Tiwari; H.S. Kar

DOI:         Access: Open Access Read More

Author(s): Minakshi Waghmare; Kalyani Kale; Deepti Bhagchandani; Shekhar Waikar

DOI:         Access: Open Access Read More

Author(s): Ram Kumar Sahu; Pushpa Prasad; Shashikant Chandrakar; Amit Roy

DOI:         Access: Open Access Read More

Author(s): Swapnil Deshmukh; Nikhil Chawala; Atharv Bhide; Shekhar Waikar

DOI:         Access: Open Access Read More

Author(s): Roshan Ramteke; Simran Kukreja; Shruti Motwani; Arti Shanware

DOI:         Access: Open Access Read More

Author(s): Sandhya Chandrakar; AK Gupta

DOI:         Access: Open Access Read More

Author(s): Roshan Shahu; Bhavana Hirudkar; Shekhar Waikar; Arti Shanware

DOI:         Access: Open Access Read More

Author(s): Shital Nikhar; Shivani Dani; Pranita Kale; Shekhar Waikar; Rajesh Limsay

DOI:         Access: Open Access Read More

Author(s): Suman Shrivastava; S J Daharwal

DOI:         Access: Open Access Read More

Author(s): Alpana Ram

DOI:         Access: Open Access Read More

Author(s): Rakhi Sarpate; Priyanka Bhaisare; Poonam Patil; Arti Shanware

DOI:         Access: Open Access Read More