Abstract View

Author(s): Vishal Jain

Email(s): vishaljain123@gmail.com

Address: University Institute of Pharmacy, P. Ravishankar Shukla University, Raipur - 492 010, India.

Published In:   Volume - 29,      Issue - 1,     Year - 2016

DOI: Not Available

WHO is highly recommended the customary exploitation of traditional therapeutics of medicinal plants and is consequently in pipeline for development of monograph and exploring their uncultivated pharmacological properties. Presently, correct identification of medicinal plants by phytochemical fingerprints is a speedy tool to ensure reproducible quality of herbal drugs. In our study, the ethyl acetate and methanol extract of leaves of Lannea coromandelica (L. coromandelica) was subjected for chemical fingerprint as well therapeutic aid as antifilarial agents. Ethyl acetate and methanolic extract of leaves of L coromandelica was prepared using buchi speed extractor. High performance thin layer chromatography (HPTLC) was employed to develop chemical fingerprint and filariciadal activity of ethyl acetate and methanol extract was assessed by motility inhibition and MTT reduction assay with concentrations range 1000 to 25ug/ml. The HPTLC analysis of ethyl acetate and methanol extract was carried out using hexane: ethyl acetate: formic acid: methanol (5:4:1:0.5 v/v/v/v) for fingerprinting and quantification ellagic acid and quercetin. The HPTLC method was found to give compact spots for Rf = 0.54 and 0.51 ellagic acid; Rf = 0.91 and 0.87 quercetin for ethyl acetate and methanol extract respectively. The HPTLC method was validated as per the ICH guidelines. Inhibitory concentration (IC) for the ethyl acetate and methanol extract was found to be 284.5ug/ml and 312.3ug/ml respectively. In motility assay, complete inhibition of motility was observed for all concentrations. Hence, our study could be valuable for inventing strategies for quality control parameter and justifies the ethnic uses of plant in folkloric medicines.

Cite this article:
Jain (2016). Chemical Fingerprint Analysis and Pharmacological Evaluation of Leaf of Lannea coromandelica Linn. Journal of Ravishankar University (Part-B: Science), 29(1), pp.153-154.

References not available.

Related Images:

Recent Images

Performance Evaluation of Spectrogram Based Epilepsy Detection Techniques Using Gray Scale Features
Perovskite Solar Cells an Efficient, Low Cost, Emerging Photovoltaic Technology
Spectrophotometric Determination of Phenthoate in Vegetables and Fruit Samples of Kabirdham (Chhattisgarh)
Flotation-Dissolution-Spectrophotometric Determination of Phorate in Various Environmental Samples
Preparation, Fabrication and Characterization of Sol-Gel ZnO Thin Films for Organic Solar Cells
Distribution of Some Selected Surface Active Agents (SAAs) in the Aquatic and Global Environment with Their Toxic Impact: A Comprehensive Review
Intriguing Clinical and Pharmaceutical Applications of IERs: A Mini Review
Soil Contamination in the Industrial Vicinity of Bemetara and Raipur District of Chhattisgarh, India
An Extractive Spectrophotometric Method for the Determination of Pymetrozine in Various Ecological Samples of Bilaspur District (C.G.)
Development and Characterization of Quercetin Loaded Nanoparticle for Skin Cancer


Recomonded Articles:

Author(s): Suman Shrivastava, Pooja Deshpande, S. J. Daharwal*

DOI: 10.52228/JRUB.2018-31-1-6         Access: Open Access Read More

Author(s): Deepak Kumar Sahu; Joyce Rai; Chhaya Bhatt; Manish K. Rai*; Jyoti Goswami; Ajay Kumar Sahu; Thakur Vikram Singh; Mamta Nirmala; Kalpana Wani and Prashant Mundeja

DOI: 10.52228/JRUB.2018-31-1-1         Access: Open Access Read More

Author(s): Pooja Deshpande, Suman Shrivastava, S.J. Daharwal*

DOI: 10.52228/JRUB.2018-31-1-7         Access: Open Access Read More

Author(s): Akhilesh Kumar Tiwari*

DOI: 10.52228/JRUB.2019-32-1-7         Access: Open Access Read More

Author(s): AR Sood and RC Rathor

DOI:         Access: Open Access Read More

Author(s): JK Nandagawe; PK Patil; RD Lawangar-Pawer

DOI:         Access: Open Access Read More

Author(s): A P Kashid; R T Patil; N B Patil; S H Chavan

DOI:         Access: Open Access Read More

Author(s): A.K. Agarwal; S. Upadhyay; P.C. Mahajan

DOI:         Access: Open Access Read More

Author(s): Swarnlata Saraf; Shailendra Saraf

DOI:         Access: Open Access Read More

Author(s): Manas Kanti Deb; Mithlesh Mahilang; Jayant Nirmalkar

DOI: 10.52228/JRUB.2017-30-1-2         Access: Open Access Read More

Author(s): Princy Dugga; Shamsh Pervez; Rakesh Kumar Sahu; Madhuri Verma; Shahina Bano; Manas Kanti Deb

DOI: 10.52228/JRUB.2017-30-1-5         Access: Open Access Read More