Roshan Ramteke, Simran Kukreja, Shruti Motwani, Arti Shanware
Gurunanak College of pharmacy, Deepak Nagar, Behind C.P. Foundary, Nari Road, Nagpur 440 026, India
Rajiv Gandhi Biotechnology Center, Laxminarayan Institute of Technology, Amravati Road, Nagpur - 440 026, India.
Volume - 29,
Issue - 1,
Year - 2016
The plants of the genus Tephrosia purpurea Linn are commonly called as Sharapunkha in Ayurvedic system of medicine belonging to the family Fabaceac. The aerial parts are widely used as anthelmintic, bitter-tonic, blood purifier etc. The plant was found to be rich in flavonoids, rutin, and quercetin. Several compounds including flavonoids, lignans, polyphenols, alkaloids, triterpenes were isolated from these plants & some of them interacts with most of the key enzymes. Various pharmacological studies were carried out with the extracts & purified compounds. The survey of literature has revealed that the flavonoid rich fraction of the plant has not been investigated for the anti-microbial activity. The aerial parts of Tephrosia purpurea were collected from the local Nagpur region. It was identified by the Department of Botany, RTM Nagpur University, Nagpur with the help of authentic herbarium species. In the present investigations the material was dried in shade and then coarsely powdered and was used for the extraction of total flavonoid fraction. The dried aerial part was defatted with the help of petroleum ether (60°-80°) & the marc was used to isolate flavonoid rich fraction. The flavonoid rich fraction was evaluated qualitatively for the presence of flavonoid with the help of preliminary phytochemical test and Thin Layer Chromatography. The fraction was then evaluated for the anti-microbial activity with the help of Gram-positive, Gram- negative bacteria and Fungi.
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Cite this article:
Ramteke, Kukreja, Motwani and Shanware (2016). Evaluation of Anti-Microbial Activity of Flavonoid Rich Fraction of Aerial Parts of the Plant Tephrosia purpurea Linn. Journal of Ravishankar University (Part-B: Science), 29(1), pp.182-183.