Atmospheric and hydrological processes and indiscriminate direct discharges have transformed the aquatic environment to an ultimate sink for environmental pollution. Fish may be exposed to chemicals by different routes, for long period of time and also bioaccumulate and biomagnify toxins from their environment to extremely high levels. Because of great similarities existing between mammalian and fish immune functions, they are used as model organisms to indicate possible effects of toxicants on humans. The present study consists of toxic effects of different concentrations of sodium fluoride during both short and long term exposure on total protein and A/G ratio of Clariasbatrachus under laboratory conditions. Results indicate concentration and duration of exposure induced changes in both. In the present work, a rapid percent decline in A/G ratio and total protein of fishes in the first 24 hours during acute exposure to sodium fluoride possibly reflects overproduction of globulins, such as seen in autoimmune diseases. Increase in A/G ratio observed during chronic exposure, possibly suggests underproduction of immunoglobulins and reflects inhibition of antibody production.
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Cite this article:
Sahu and Poddar (2016). Effect of Sodium Fluoride on Total Protein and Albumin Globulin Ratio of Clariasbatrachus (Linn.) 1758. Journal of Ravishankar University (Part-B: Science), 29(2), pp.11-16.