Abstract View

Author(s): Angkita Sharma, Loxmi Jamoh, Pallabi K. Hui, Hui Tag

Email(s): ankitasharmal411@gmail.com

Address: Plant Systematic and Pharmacognosy Research Laboratory, Department of Botany, Rajiv Gandhi Univerity.Rono Hills. Doimukh, hanagar-791112, Arunachal Pradesh, India
Department of Bictechnology & Chemical Engineering.National Institute of Technology.Yupia 791112. Arunachal Pradesh. India.

Published In:   Volume - 29,      Issue - 1,     Year - 2016


Paris polyphylla Smith (Melanthiaceae) is a perennial herb used in the treatment of Cancer and Alzheimer's disease. Traditionally, this plant is used as an anti-oxidant and anti-microbial agent by some local tribes of Arunachal Pradesh. The aim of the study was to evaluate the pharmacological potential with special reference to the pychopharmacological, antipyretic and analgesic activities of Rhizoma paridis (rhizome of Paris polyphylla) crude extracts collected from Dirang, West Kameng district of Arunachal Pradesh (Latitude: N 27 21' 30.39; Longitude E 92 14 27.2) in in-vive rat models and to validate the active phytoconstituents responsible for such pharmacological activities. Methanolic extract of the rhizome was induced in Wistar Albino rats weighing from 100-200g for pharmacological and phytochemical studies. The studies revealed the effectiveness of methanolic extracts of Rhizoma Paridis on phenobarbitone induced sleeping time with the maximum sleeping time of 109 2e13 minutes with a dose level of 300mg/Kg which was higher than the standard chlorpromazine drug Anti-pyretic study revealed that the extract had the capacity to reduce fever with the maximum reduction of 38.01s0.49 C to 36.2:0.53 C, with a dose level of 300mg/Kg which was comparable with paracetamol drug. The analgesic study revealed that the percentage inhibition for acetic acid induced writhing number of the extract was 80 with a dose level of 300mg/Kg which was higher than standard ibuprofen drug. The phytochemical study through qualitative, quantitative and GC-MS analysis confirmed the presence of relevant compounds which are probably synergistically responsible for psychopharmacological, antipyretic and analgesic properties. The results were analyzed and compared statistically using Origin 8 software. The pharmacological efficacies of the root extract of Paris polyphylla Smith from Arunachal Pradesh shown in the present study validates the local claims about traditional uses of the plant against certain ailments.

Cite this article:
Not Available

References not available.

Related Images:

Recent Images

Potential of Bioactive Compounds for Atopic Dermatitis
Time-Frequency Image-based Speech Emotion Recognition using Artificial Neural Network
Zn Fortification Influential Impact on the Productivity of Calocybe indica Mycelium
Enhanced ACO in clustering algorithm for QoS in WSN enabled IoT
A Modified Regression Type Estimator Using Two Auxiliary Variables
Sziklai Pair based Small Signal Amplifier with BJT-MOSFET Hybrid Unit at 180nm Technology
Rice Straw-Derived Carbon Integrated with PANI: As an Electrode Material for High-performance Supercapacitor
Extraction, Characterisation, Biological Properties and Applications of Essential Oils: A Review
Biopolymeric Materials in the Management of Diabetic Wound Healing: A Comprehensive Review
Entomopathogenic Fungi: Nature


Recomonded Articles: