Till date snake venom is a serious public health hazards in tropical countries especially in India. Snake venom, is much complex of all poisons is a mixture of enzymatic and non-enzymatic toxic compounds as well as other non-toxic proteins, carbohydrates and metals. Presently the only available treatment is usage of anti-venom against snake bite. Another important aspect is, in almost all parts of the world numerous medicinal plant species are used as folk medicine to treat snake bite. In present study, an attempt of scientific validation of traditional knowledge has been carried out. Three plant species viz. Pandanus candelabrum, Eclipta prostrata and Sphagneticola trilobata have been selected for study on the basis of knowledge practice of traditional healers of Chhattisgarh state of India. In present study some lead compound were found established anti-venom property viz. 2-OH-4-methoxy benzoic acid from Pandanus candelabrum, Wedelolactone from Sphagneticola trilobata and Sitosterol and Stigmasterol from Eclipta prostrata.
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