Abstract View

Author(s): Bharati Verma, Rama Pande

Email(s): bharati22july@gmail.com

Address: School of Studies in Chemistry, Pt. Ravishankar Shukla University, Raipur - 492010, India.

Published In:   Volume - 29,      Issue - 1,     Year - 2016

DOI:

ABSTRACT:
Radical scavenging and metal reducing power of small molecules are very important in the development of new therapeutic reagents. N-Arylhydroxamic acids are neutral polyfunctional molecules, with pharmacophoric functionality,- NOH.C=O in their structure. The four different hydroxamic acid derivatives, N-p-tolyl-4- ethoxybenzo, N-o- tolyl-4- ethoxybenzo, N-m-chloro-2-methoxybenzo and N-m- chloro-4-methoxybenzo hydroxamic acids are chosen for the present study. The donor hydrogen of the hydroxyl group present in the chemical moiety of these ligands is responsible for antiradical effect. The radical scavenging activity of hydroxamic acids is estimated following the DPPH radical scavenging and DNA cleavage protection methods. Increase in absorbance with concentration in iron and copper lons Reducing Antioxidant Power Assay methods confirms that all hydroxamic acids were able to reduce ferric/cupric ion into ferrous/cuprous ion. The reducing power increases with increase in concentration of hydroxamic acids in both methods.

Cite this article:
Not Available


References not available.

Related Images:



Recent Images



Study of the Enhanced Efficiency of Crystalline Silicon Solar Cells by Optimizing Anti Reflecting Coating using PC1D Simulation
Formulation of Topical Itraconazole Nanostructured Lipid Carriers (Nlc) Gel for Onychomycosis
Cosmetic Testing Equipment: Device and Types of Equipment for Dermatological Evaluation for Women’s Skin
Oxidative stress: Insights into the Pathogenesis and Treatment of Alopecia
UV Spectroscopy Analysis for Itraconazole
Challenges and Potential of Perovskite Solar Cells
Kinetic Study of Solvent Effect on the Hydrolysis of  Mono-3, 5-Dimethylaniline Phosphate
OLED: New Generation Display Technology
Parametric study of AlGAN/GaN UV-Led Based on Quantum Confined Stark Effect (QCSE)
Analysis of High Efficient Perovskite Solar Cells Using Machine Learning

Tags


Recomonded Articles: