Abstract View

Author(s): Krishna Kumar Patel, Sarita Patel

Email(s): drkrishnabsp@gmail.com

Address: School of Studies in Chemistry. Pt. Ravishankar Shukla University, Raipur 492010
India National Center for Natural Resources, Pr. Ravishankar Shukla University, Raipur -42010, India.

Published In:   Volume - 29,      Issue - 1,     Year - 2016


Carbapenems are used for treating serious infections caused by multidrug resistant gram negative bacilli including non-fermenters (NFGNB). Stability to B-lactamases had made them the preferred drug of choice in infections with B-lactam- resistant gram negative bacteria including non-fermenting bacteria (NFGNB). The rapid dissemination of carbapenem is therapeutically challenging and necessitates effective antibiotics policies and meticulous surveillance program in a critical care setting. In a state like Chhattisgarh, where information on microbiological aspects of various infectious diseases are negligible, present study is an attempt to determine magnitude of carbapenem resistance in NFGNB recovered from patients with respiratory tract infections in the intensive care units Carbapenems have revolutionalised the treatment of potentially serious infections caused by multidrug resistant gram negative bacilli. The study confirms the occurrence of carbapenem resistance in NFGNB isolates recovered from patients with respiratory infection in the intensive care units (ICUS) A total of 676 endotracheal aspirate specimens were subjected to microbiological work-up which yielded 358 NFGNB isolates in a study conducted at a teaching hospital in tribal dominated region of Chhasttisgarh state during January 2015 to November 2015. A total of 48 NFGNB exhibited resistance to imipenem and meropenem. The carbapenem resistance was predominant with Pseudomonas aeruginosa (58.8 %). The enhanced status of NFGNB as nosocomial pathogens, simultancous with their increased resistance to carbapenems is immensely worrisome and threatens to disrupt-therapeutic approaches especially among those patients admitted to critical care units.

Cite this article:
Not Available

References not available.

Related Images:

Recent Images

Herbal Alternatives for Oral Health:  Mechanistic Exploration with their Market Potential
A Review on Extraction, Identification and Application of Pesticidal Active Phytoderived Metabolites
Determination of Total Dissolved Solids (TDS) of RO Purified Drinking Water Samples in Raipur
Time of the Day Variability in Pit-Building Behavior of Antlion Larvae
A Comprehensive Review of a particular Skin Injury: Pathogenesis, triggers, and current Treatment Options
Enhanced antioxidant activity in Curcuma caesia Roxb. microrhizomes treated with silver nanoparticles
Studies on the Interaction of Imidazolium Ionic Liquids with Human Serum Albumin
Basic and Advanced Logical Concept Derived from Surface Enhanced Infrared Spectroscopy (SEIRS) as Sensing Probe for Analysis of Chemical Species: A Brief Review
Soil Erosion Risk Estimation by using Semi Empirical RUSLE model: A case study of Maniyari Basin, Chhattisgarh
An Estimator of Population Variance Using Multi-Auxiliary Information


Recomonded Articles: