Abstract View

Author(s): Prasad A Wadegaonkar

Email(s): prasadwadegaonkare sgahu.ac.in

Address: Department of Biotechnology, Sant Gadge Baba Amravati University, Amravati 444602, India.

Published In:   Volume - 29,      Issue - 1,     Year - 2016

DOI:

ABSTRACT:
Advancement in the knowledge of molecular mechanisms, cellular biology and genomics not only increased the number of molecular targets but also demanded shorter drug discovery timelines. The chemistry of natural products has been investigated thoroughly in the recent decades, resulting in the better understandıng. Computational methods have recently shown to be an important complementary tool for study of pharmacological activity of natural compounds. Bioprocess engineering has played a successful role in developing and producing pharmaceuticals from fungal and bacterial origin. The principles of this technology have already been exploited for commercial production of vaccines and therapeutic proteins from animal origin. The potential and knowledge of Bioprocess engineering has not yet fully exploited for commercial production of biopharmaceuticals from herbal origin. Scale up of suspension cultures, tissue and organ cultures of medicinal plants can overcome most of the shortcomings of herbal medicines obtained from natural resources. Withanolides, for example can interact with variety of IAPS with distinct architecture such as BIR region. At the same time these withanolides can interact with diverse group of proteins vhich are involved in inhibition of apoptosis. The bioprocess for production of herbal biopharmaceuticals from Withania somnifera with defined chemo-profile has been developed.

Cite this article:
Not Available


References not available.

Related Images:



Recent Images



Chlorpyrifos Mediated Amendment in Protein Profiling of Bacillus spp.
Structural, Compositional and Photoluminescence Studies of Li4SrCa(SiO4)2: Eu3+ Red Phosphor Synthesized by Solid State Reaction Method
Formulation and Characterization of Magnetically Responsive Mesalamine Microspheres for Colon Targeting
Development of Non-Invasive Technique for Heart Rate Detection Using Facial Videos
Human Part Semantic Segmentation Using CDGNET Architecture for Human Activity Recognition
Lifestyle Modification Therapy and its Effect on Weight Status of Non-Alcoholic Male Liver Disease Patients
Exploring Life Cycle Analysis in Developing Sustainable Communities in Chhattisgarh
Monitoring the Concentration of Lead in the Industrial Wastewater of Baloda Bazar District
Impact of Climate Change on Paddy Yield in Bastar District of Chhattisgarh
Chemical Pollutants: A Concern to The Environment

Tags


Recomonded Articles: