ABSTRACT:
Cervical cancer has shown its silent presence in last few decades. It has been observed that the number of cervical cancer cases in women has shown a steady growth in India as well as in our state. Various herbal drugs of indigencous origin have been extensively investigated for their anticancer activity against various forms of cancer including cervical cancer also However, the major disadvantage remained their poor aqueous solubility and less extent to reach the cellular targets. In the present research, an attempt has been done to develop targeted moieties of selected anticancer herbal drugs and evaluated them in vitro. The in vitro cellular uptake and antiproliferative potentials of these targeted nanocargoes were evaluated using Hela cell lines. The study results showed a very significant activity of herbal drug loaded targeted nanocargoes as compared to conventional drug.