Cite this article:
Sahu and Poddar (2016). Effect of Sodium Fluoride on Total Protein and Albumin Globulin Ratio of Clariasbatrachus (Linn.) 1758. Journal of Ravishankar University (Part-B: Science), 29(2), pp.11-16.
Journal of Ravishankar University - B,
29 (2&3) pp. 11-16 (2016)
Effect of Sodium Fluoride on Total Protein and Albumin
Globulin Ratio of Clariasbatrachus (Linn.) 1758
Gamini Sahu and Aditi Niyogi Poddar
Parasitology
Laboratory, School of Studies in Life sciences, Pt. Ravishankar Shukla
University, Raipur-492010, India
Corresponding
author: adinpod@gmail.com
[Received 17 September 2015;
accepted 2 April 2016]
Abstract.
Atmospheric and hydrological processes and indiscriminate direct discharges
have transformed the aquatic environment to an ultimate sink for environmental
pollution. Fish may be exposed to chemicals by different routes, for long
period of time and also bioaccumulate and biomagnify toxins from their
environment to extremely high levels. Because of great similarities existing
between mammalian and fish immune functions, they are used as model organisms
to indicate possible effects of toxicants on humans. The present study consists
of toxic effects of different concentrations of sodium fluoride during both
short and long term exposure on total protein and A/G ratio of Clariasbatrachus
under laboratory conditions. Results indicate concentration and duration of
exposure induced changes in both. In the present work, a rapid percent decline
in A/G ratio and total protein of fishes in the first 24 hours during acute
exposure to sodium fluoride possibly reflects overproduction of globulins, such
as seen in autoimmune diseases. Increase in A/G ratio observed during chronic
exposure, possibly suggests underproduction of immunoglobulins and reflects
inhibition of antibody production
Keywords:
Total protein, A/G ratio,
immunsuppression, autoimmune
disorder.
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