Cite this article:
Jadhav (2016). Study of Antibacterial Activity of Medicinal Plants on Dental Caries Inducing Multi Drug Resistant (MDR) Streptococcus mutans. Journal of Ravishankar University (Part-B: Science), 29(1), pp.83-84.
OP-CI5
Study of
Antibacterial Activity of Medicinal Plants on Dental Caries Inducing Multi Drug
Resistant (MDR) Streptococcus mutans
R N Jadhav
Shivneri Mahavidyalaya,
Shirur-Anantpal, MS, India
Corresponding author email: ramchandrajadhav17@yahoo.in
[Received
7 February 2016; accepted 8 February 2016]
Abstract: Dental caries
is the disease of the calcified tissues of the teeth characterized by
demineralization of the inorganic portion and destruction of the organic
substances of the teeth, which leads to cavitations. Streptococcus mutans is
Gram positive spherical shaped bacterium. It is the normal flora of oral
cavity. The bacterium has a polysaccharide coat that allows to stick to teeth
and also to damage heart valves. It also produces acid from sugar in saliva
which promotes erosion of tooth enamel. The indiscriminate use of antibiotics
has led to an increase in antibiotic resistance among microorganisms. Bacteria
become resistant to antibiotic by different ways. R-plasmid often contains
genes for resistance to several antibiotics. Plasmid can be transferred between
bacterial cells in a population and between different but closely related
bacterial populations. Patent suffering from antibiotic resistant strain fail
to respond antibiotic treatment. So there is a continuous demand of new drug.
In the present study antibacterial activity of Allum sativum, Cinnamon
zeyanicum and Syzium aromaticum was studied against dental caries inducing MDR
StreptococcuS mutans. Isolation and identification of Streptococcus mutans was
done by morphological, cultural characteristics and standard biochemical tests.
Antibiotic susceptibility testing was performed by Kirby Bauer's disc diffusion
method. The most common pattern of multiple drug resistance of isolates of
Streptococcus mutans observed was amoxycillin-ampicillin-tetracyclin-nalidixic
acid. Antibacterial activity of medicinal plant is studied by agar (well)
diffusion method. It was found that Allum sativum showed highest antibacterial
activity, Cinnamon zeyanicum and Syzium aromaticum showed moderate
antibacterial activity.
Keywords: Antibacterial
activity. Disc diffusion method. Multi drug resistant, Plant extracts,
Streptococcus mutans