Author(s):
Debarshi Kar Mahapatra, Manish Kamble, Ruchi Shivhare, Kavita Pandey
Email(s):
mahapatradebarshi@gmail.com
Address:
Department of Pharmaceutical Chemistry, Kamla Nehru College of Pharmacy, Nagpur 440026, India
Department of Pharmacognosy, Kamla Nehru College of Pharmacy, Nagpur - 440026, India.
Published In:
Volume - 29,
Issue - 1,
Year - 2016
Cite this article:
Mahapatra, Kamble, Shivhare and Pandey (2016). In Vitro Anti-Inflammatory Study of Tridax Procumbens L Leaf, Stem, Root, and Flower Extracts. Journal of Ravishankar University (Part-B: Science), 29(1), pp.196.
PP-F36
In Vitro
Anti-Inflammatory Study of Tridax Procumbens L Leaf, Stem, Root, and Flower
Extracts
Debarshi Kar Mahapatra, Manish
Kamble, Ruchi Shivhare and Kavita Pandey
Department of Pharmaceutical
Chemistry, Kamla Nehru College of Pharmacy, Nagpur 440026, India
Department of Pharmacognosy,
Kamla Nehru College of Pharmacy, Nagpur - 440026, India
Corresponding author email:
mahapatradebarshi@ gmail.com
[Received
14 January 2016; accepted 20 January 2016]
Abstract: Tridax
procumbens L. is a traditional plant known for its anti-inflammatory activity,
however, many literatures have reported the potentiality, but the actual vital
portion where the liable phytoconstituents are present is still debated. In
order, to determine the same, in vitro anti-inflammatory activity of Tridax
procumbens L. plant part (leaf, stem, root, and flower) extracts (aqueous, ethanol,
methanol, chloroform and petroleum ether) were investigated by human red bold
cell membrane stabilization (HRBCM) method. All the plant part extracts showed
moderate to significantly high activity. The alcoholic leaf extract (ethanol
and methanol) demonstrated noteworthy HRBCM stabilization activity at 200 ug/mL
(69.68%, and 70.44%) compared to standard drug diclofenac sodium (81.37%).
Moreover, the extracts displayed considerable anti- inflammatory potential. The
result of the study revealed the traditional importance of this plant in
inflammation.
Keywords:
Anti-inflammatory, Phytoconstituents, HRBCM method