PP-F19

Pharmacognostical, Phytochemical Screening, Free Radical Scavenging Assay and Cytotoxicity Studies on Baeolepis nervosa (Wight & Arn.) Decne. Ex Moq

R Logesh, Amrendra Kumar Tiwari, Pritorthi Bhattacharjee, Pulok K Mukherjee and S Rajan

School of Natural Products Studies, Jadavpur University, Kolkata - 700 032, India

School of Natural Product Studies, Jadavpur University, Kolkata - 700 032, India

Ministry of Ayush, Govt. of India, Indra Nagar, Emerald 643 209, India

Corresponding author email: elogesh14@ gmail.com

[Received 19 January 2016; accepted 29 January 2016]

Abstract: To study the pharmacognostical aspect of the medicinal plant Baeolepis nervosa. To study the phytochemical aspects of the medicinal plant and to find the secondary metabolites present. To do the fractionation of the mother extract and subjected for Free radical scavenging assay. To study the anti-microbial properties of B. nervosaon mother extract. To determine the cytotoxic property for Potentanti-oxidant extracts. Thepharmacognostical studies were performed using Photomicrography. The mother extract was subjected for preliminary phytochemical analysis and Anti-microbial studies. The Fractionation (Liquid-Liquid) of the mother extract was carried outusing.(Pet ether, choloform, ethyl acetate and aqueous) and was subjected to Free radical scavenging assay using DPPH, ABTS, NO, and H;O, To determine the cytotoxic property for Potentanti-oxidant extracts on selected cell line (Particularly, HaCaT and A549). The extraction and fractionation was done and the percentage yield was calculated. The plant showed potent anti-oxidant activity on all the assay methods. Some extracts showes better anti-baterial activity, but there was no ant-fungal activity found. The cytotoseity studics showed moderate or average activity on both the cell lines (HaCaT and AS49).

Keywords: Barolepis nervosa, Cytotoric, Photomicrography