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Author(s): Swapnil Deshmukh, Nikhil Chawala, Atharv Bhide, Shekhar Waikar

Email(s): manishnivsarkar@gmail.com

Address: Gurunanak College of pharmacy, Deepak Nagar, Behind C.P. Foundary, Nari Road, Nagpur 440 026, India.

Published In:   Volume - 29,      Issue - 1,     Year - 2016


Cite this article:
Deshmukh, Chawala, Bhide and Waikar (2016). Evaluation of Anti-Microbial Activity of Flavonoid Rich Fraction of Aerial Parts of the Plant Fagonia arabica. Journal of Ravishankar University (Part-B: Science), 29(1), pp.185-186.



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Evaluation of Anti-Microbial Activity of Flavonoid Rich Fraction of Aerial Parts of the Plant Fagonia arabica

Swapnil Deshmukh, Nikhil Chawala, Atharv Bhide and Shekhar Waikar

Gurunanak College of pharmacy, Deepak Nagar, Behind C.P. Foundary, Nari Road, Nagpur 440 026, India

Corresponding author email: manishnivsarkar@ gmail.com

[Received 06 January 2016; accepted 28 January 2016]

Abstract: The plants Fagonia arabica belonging to the family Zygophyllaceac commonly called as Dhamasa has long been used in the traditional system of medicine.the aerial parts are used as astringent, bitter-tonic, febrifuge and prophylactic against smallpox. Several compounds including flavonoids, lignans, polyphenols, alkaloids, triterpenes were isolated from these plants & some of them interacts with most of the key enzymes. Various pharmacological studies were carried out with the extracts & purified compounds. The survey of literature has revealed that the flavonoid rich fraction of the plant has not been investigated for the anti-microbial activity. The aerial parts of Fagonia arabica were collected from the local Nagpur region. It was identified by the Department of Botany; RTM Nagpur University, Nagpur with the help of authentic herbarium species. In the present investigations the material was dried in shade and then coarsely powdered and was used for the extraction of total flavonoid fraction. The dried aerial part was defatted with the help of petroleum ether (60°-80°) & the mare was used to isolate flavonoid rich fraction. The flavonoid rich fraction was evaluated qualitatively for the presence of flavonoid with the help of preliminary phytochemical test and Thin Layer Chromatography. The fraction was then evaluated for the anti-microbial activity with the help of Gram-positive, Gram- negative bacteria and Fungi.

Keywords: Fagonia arabica, Flavonoids, Thin Layer Chromatography, Anti-microbial activity


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