Author(s):
Swapnil Deshmukh, Nikhil Chawala, Atharv Bhide, Shekhar Waikar
Email(s):
manishnivsarkar@gmail.com
Address:
Gurunanak College of pharmacy, Deepak Nagar, Behind C.P. Foundary, Nari Road, Nagpur 440 026, India.
Published In:
Volume - 29,
Issue - 1,
Year - 2016
Cite this article:
Deshmukh, Chawala, Bhide and Waikar (2016). Evaluation of Anti-Microbial Activity of Flavonoid Rich Fraction of Aerial Parts of the Plant Fagonia arabica. Journal of Ravishankar University (Part-B: Science), 29(1), pp.185-186.
PP-F18
Evaluation of
Anti-Microbial Activity of Flavonoid Rich Fraction of Aerial Parts of the Plant
Fagonia arabica
Swapnil Deshmukh, Nikhil Chawala,
Atharv Bhide and Shekhar Waikar
Gurunanak College of pharmacy,
Deepak Nagar, Behind C.P. Foundary, Nari Road, Nagpur 440 026, India
Corresponding author email:
manishnivsarkar@ gmail.com
[Received
06 January 2016; accepted 28 January 2016]
Abstract: The plants
Fagonia arabica belonging to the family Zygophyllaceac commonly called as
Dhamasa has long been used in the traditional system of medicine.the aerial
parts are used as astringent, bitter-tonic, febrifuge and prophylactic against
smallpox. Several compounds including flavonoids, lignans, polyphenols,
alkaloids, triterpenes were isolated from these plants & some of them
interacts with most of the key enzymes. Various pharmacological studies were
carried out with the extracts & purified compounds. The survey of
literature has revealed that the flavonoid rich fraction of the plant has not
been investigated for the anti-microbial activity. The aerial parts of Fagonia
arabica were collected from the local Nagpur region. It was identified by the
Department of Botany; RTM Nagpur University, Nagpur with the help of authentic
herbarium species. In the present investigations the material was dried in
shade and then coarsely powdered and was used for the extraction of total
flavonoid fraction. The dried aerial part was defatted with the help of
petroleum ether (60°-80°) & the mare was used to isolate flavonoid rich
fraction. The flavonoid rich fraction was evaluated qualitatively for the
presence of flavonoid with the help of preliminary phytochemical test and Thin
Layer Chromatography. The fraction was then evaluated for the anti-microbial
activity with the help of Gram-positive, Gram- negative bacteria and Fungi.
Keywords: Fagonia arabica, Flavonoids, Thin Layer Chromatography, Anti-microbial
activity