PP-F15

Formulation and Evaluation of Flavonoid Rich Fractions of Different Varieties of Turmeric for their Antifungal and Antibacterial Activity

Dipika R Kalambe, AH Deshpande, SB Waikar and A Shanware

Gurunanak College of Pharmacy, Nari Road, Nagpur 440 026, India

Rajiv Gandhi Biotechnology Center, Laxminarayan Institute of Technology, Amravati Road, Nagpur 440 026, India

Corresponding author email: kalambhedipika@ gmail.com

[Received 15 January 2016 accepted 29 January 2016]

Abstract: Flavonoid science is a research area rapidly gaining deeper inside on health benefit and chemical properties of flavonoids. Many have low toxicity in mammals and some of them are widely used as medicine as flavonoids exhibit several biological effects such as antincoplastic, anti-inflammatory, antihepatotoxic, antiulcer activity, etc. Three varieties of turmeric grown in the local Nagpur region were collected, authenticated and subsequently dried in shade. The material was defatted and the flavonoid rich fractions were isolated from each variety by the established method. The fractions were evaluated qualitatively with the help of chemical tests and thin layer chromatography. These fractions will be further evaluated for their antibacterial activity and antifungal activity. The flavonoid rich fractions will be formulated into topical dosage form followed by evaluation of these dosage forms.

Keywords: Curcuma longa, Flavonoids, Antifungal activity, Antibacterial activity