Author(s):
Gunjan Kalyani, Rahul Singh, Nishtha Vaidya, Rashmi Dwivedi, Kamlesh Dadsena, Neeraj Kumar Verma, Arun Singh Parihar, Atanu Kumar Pati, Mitashree Mitra
Email(s):
mitashree.mitra@gmail.com
Address:
National Center of Natural Resources (NCNR), PRSU, Raipur 492 010, India
School of Life Sciences, Pt. Ravishankar Shukla University, Raipur 492 010, India
School of Studies in Anthropology, Pt. Ravishankar Shukla University, Raipur - 492 010, India.
Published In:
Volume - 29,
Issue - 1,
Year - 2016
Cite this article:
Kalyani, Singh, Vaidya, Dwivedi, Dadsena, Verma, Parihar, Pati and Mitra (2016). Quest for Bioactive Phytomolecules against Psoriasis based on Traditional Healing Practices in Chhattisgarh, India. Journal of Ravishankar University (Part-B: Science), 29(1), pp.170-171.
PP-E15
Quest for
Bioactive Phytomolecules against Psoriasis based on Traditional Healing
Practices in Chhattisgarh, India
Gunjan Kalyani, Rahul Singh,
Nishtha Vaidya, Rashmi Dwivedi, Kamlesh Dadsena, Neeraj Kumar Verma, Arun Singh
Parihar, Atanu Kumar Pati and Mitashree Mitra
National Center of Natural
Resources (NCNR), PRSU, Raipur 492 010, India
School of Life Sciences, Pt.
Ravishankar Shukla University, Raipur 492 010, India
School of Studies in
Anthropology, Pt. Ravishankar Shukla University, Raipur - 492 010, India
Corresponding author email: mitashree.mitra@gmail.com
[Received
03 February 2016, accepted 05 February 2016]
Abstract: Psoriasis is
a disorder that leads to scaling and inflammation of skin accompanying pain,
swelling, redness and heat. The process of skin turnover can happen in just few
days resulting in to piling up on the skin surface. Anyone can suffer from this
disease, but it is more prevalent in adults. It affects male and female in
equal rate.The prevalence of psoriasis reported in India is 0.44 - 2.8 %.
However, there is complete paucity of information on its prevalence in
Chhattisgarh. The objective of the present research was to survey tribal
population to map prevalence of Psoriasis and to document traditional knowledge
(TK) on the health care usages against Psoriasis that have been adopted by indigenous
community of Chhattisgarh. The map of Chhattisgarh was digitized and laid 10 x
10 km' grids overlying forested areas inhabited by the tribes. We randomly
selected four districts, namely Mahasamund, Raigarh, Jashpur and Surguja as our
study siles. we conducted the field survey involving 5094 households that
included 19299 subjects. We used specially designed inventory for primary
detection of psoriasis. Simultaneously we interviewed 45 traditional healers
and also the psoriasis patients in order to document the herbs and parts
thereof traditionally used for curative purposes and their efficacy. We also
inquired about the herbal formulations recommended by the traditional healers
and brought those formulations to our laboratory for phytochemical screening.
This study has been approved by the Institution Ethics Committee (IEC) for
Human Research of P. RavishankarShukla University, Raipur, India. The analysis
of data revealed that the percentage prevalence of psoriasis in the designated
study areas is 0.12 %. We interviewed 45 local healers and discovered that a
large number of herbs, 28 species belonging to 25 families, are used for curing
psoriasis in the form of 29 formulations. It was a gigantic task to identify
the exact bioactive phytomolecules working against psoriasis. A detailed matrix
was constructed and it was revealed that in most of the plant species belonged
to family Combretaceae, Asteraceae, Agavaceae, Anacardiaceae, Euphorbiaceae,
Fabaceae etc. Most frequently used plant species used in the herbal
formulations were Semecarpus anacardium Linn, Agave Americana, Abrus
precatorius L., Terminalia arjuna (DC) Wight & Am. etc., in diverse media,
such as water, sesame oil, camphor coconut oil. The sesame oil was the most
preferred medium. Currently the work in under progress to mark out the exact
phytochemical(s) that could be implicated for curing psoriasis. This work will
help in the discovery of potential therapeutic molecule(s) for curing
psoriasis.
Keywords: Psoriasis,
Traditional healers, Medicinal plants, Bioactive phytomolecules