Cite this article:
Shende, Itankar and Prasad (2016). Jaatyadi Ghrita: As Potent Wound Healing Agent Indiabetic Animal Model. Journal of Ravishankar University (Part-B: Science), 29(1), pp.149.
PP-C10
Jaatyadi Ghrita:
As Potent Wound Healing Agent Indiabetic Animal Model
PR Shende', PR Itankar and SK
Prasad
Department of Pharmaceutical
Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur -44O 033,
India
Corresponding author email:
priyankashende128@gmail.com
(Received
01 February 2016; accepted 02 February 2016)
Abstract: Diabetes is
a disease of altered glucose homeostasis and persistent hyperglycemia leading
to advanced glycation end product (AGE) which are primarily responsible for the
damage of cells which have a slow turn over (like neuronal tissue). This
abnormality results in poor wound healing. Further hyperglycemic complication
leads to wound infection. Wound management is a significant and growing health
burden on the community. In the Indian context, the formal descriptions of
wound care have been vividly elaborated in the three great treatises
(Brahatrayi) of Ayurveda viz. Charaka Samhita, Sushruta Samhita and Astanga Sangraha.
Some of the herbal drugs with proven antidibetic and wound healing activity are
Jaati (Jasminum officinale linn), Neem (Azadirachta indica AJuss), Patol
(Trichiosanthes dioica. Rozb) and Haridra (Curcuma longa linn.). The present
work is aimed to standardize and to evaluate the diabetic wound healing
activity of polyherbal formulation, JAATYADI GHRITA contain these herbs. The
work also includes Evaluation of Physicochemical Parameters, Phytochemical
screening, and Quantitative estimation of identified phytoconstituents using
HPTLC & HPLC analysis and in-vitro antimicrobial studies. This will act as
a referential source of information for researchers who have interest in the
relevant field.
Keywords: Diabetic
wound healing, JAATYADI GHRITA, HPTLC &HPLC analysis