Cite this article:
Shukla, Roy and Sharma (2016). Effect of Extracts of Some Medicinal Plants on In-Vitro Dissolution of Gallstones. Journal of Ravishankar University (Part-B: Science), 29(1), pp.125-126.
Effect of Extracts
of Some Medicinal Plants on In-Vitro Dissolution of Gallstones
Preety Shukla, Anindita Roy and
Shubha R Sharma
Department of Bio-Engineering.
Birla Institute of Technology, Mesra, Ranchi - 835 215, India
Corresponding author email: email@example.com
28 January 2016; accepted 2 February 2016]
problems especially gall stones have affected man from time immemorial. During
the time when surgery was not invented, this was mainly treated by herbal
decoctions and diet control. There has been a mention of medicinal herbs
effective in treatment of gallstones in the ancient medical records of all
cultures like Indian (Ayurvedic), Chinese (TCM), Greek (Yunani) etc. Even
today, traditional medicines are used in many households. Though there has been
extensive proof of their effectiveness in treatment of gallstones, there is a
dearth of scientific literature recording their administration trials and
effect on gallstones in vivo and in vitro. Our work was to identify some herbs
that are indigenous to this region, available easily, are said to be effective
in dissolving gallstones and also to study the effectiveness of their extract
in dissolution of the gallstones collected from the government hospitals of
Ranchi. In this way we can find a substitute for the surgical methods of
removal of gallstones which have several problems and side effects. We had
collected and dried sufficient biomass (leaves and stem) for work on 3 herbs-
Bhuiamla or break-stone herb (Phyllanthus amarus), Pudina or Mint (Mentha spp)
and Chiraita (Swertia chiraita). Solvent extracts using distilled water and the
solvents- ethanol, acetone, n-hexane and petroleum ether were prepared.
Cholesterol and pigmented gallstones were studied for this purpose. The study showed
considerable amount of dissolution of gallstones for the acetone and n-hexane
extracts of pudina, chiraita and n-hexane extract of bhumiamla.
Herbs, Extract. Chiraita