Cite this article:
Saraf and Saraf (2010). Marinosomes a Potential Vesicular System for Drug Delivery. Journal of Ravishankar University (Part-B: Science), 21(1), pp. 1-9.
Journal of Ravishankar University-B,
21(1), pp.1-9 (2010)
Marinosomes a Potential Vesicular System for Drug Delivery
Saraf and Shailendra Saraf*
University Institute of
Pharmacy, Pt. Ravishankar
Shukla University, Raipur, 492010,
Corresponding author:* email@example.com
Abstract: liposomes are
generally considered as models for biological membranes and drug delivery
systems when encapsulation and protection of hydrophilic and/or lipophilic
substances are required. Marinosomes are liposome based on a natural Marine
Lipid extract containing a high poly and saturated fatty acid. Marine
phospholipids contain a higher amount of n-3 polyunsaturated fatty acid (PUFA)
mainly eicosapentaenoic (EPA, 20:5n-3) decosahexaenoic acid (DHA, 20:6n-3),
which has documented beneficial effect on human health. The health benefits of
n-3 polyunsaturated fatty acid includes reduced inflammatory and coronary heart
disease reduced susceptibility to mental illness and improved brain and eye
function in infants. These marinosomes have good stability upon large pH change
regarding both, their physical and chemical bilayer integrities. When marinos
homes containing dietary lipids were administered orally and adequate Leopard
water interface was created by mixing of bile salt and Marine phospholipids
which plays an important role in the intestinal absorption of dietary lipids.
Marinosomes in gastric pH undergoes instantaneous physical aggression, which
was partially reversible when the external medium was further neutralized. As a
whole, this review pointed out that marinosomes may constitute an
attractive material for drug delivery and drug targeting.
Keywords: Liposomes, Poly unsaturated
fatty acids, Lipids, Marine phospholipids.
NOTE: Full version
of this manuscript is available in PDF.