Cite this article:
Ghosh and Krishnanl (1993). Kinetic solvent Deuterium effect on Hydrolysis of unsubstituted Hydroxamic Acids. Journal of Ravishankar University (Part-B: Science), 6(1), pp. 37-41.
Journal of Rallishankai University,Vol,6. No.8(Science)1993 pp 37-41
Kinetic solvent Deuterium effect on Hydrolysis of unsubstituted Hydroxamic Acids
Kallol K.Ghosh and
Klshoae K Krishnanl
School of Studies in Chemistry, Pt. Ravishankar Shukla University, Raipur-492010 (M.P.)
Ms: Received 14-8-93, Accepted 13.10.93
Abstract. The kinetic solvent
isotope effects on the acid catalysed hydrolysis of three unsubstituted hydroxamic acids of the type R-C6H4.CO NHOH (R=H, 4-CH3O and 3-Cl) have been studied
and DCl in 10% (v/v) dimethyl
sulphoxide at 550c. The results particularly the change in the magnitude
of kinetic solvent
effect on increasing acidityare consistent with a reaction
involving a· fast pre-equilibrium followde by bimolecular deuterium oxide or water attack
as a nucleophile on protonated
species of hydroxamic acid.
words: Hydroxamic Acid, Solvent Isotope Effect, Acid-Catalysis.
NOTE: Full version
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